Literature DB >> 2763266

The interactions of factors X and IX with phospholipid.

J W Bloom1.   

Abstract

The interactions of human factors X and IX with phospholipid were studied with an ELISA system. In the presence of calcium ions, factor X bound to phosphatidylserine with an affinity of 1.56 x 10(10) M-1 and to phosphatidylcholine with an affinity of 5.6 x 10(9) M-1. In the presence of calcium ions, factor IX bound to phosphatidylserine with an affinity of 8.4 x 10(8) M-1 and no binding to phosphatidylcholine was observed. No competition of factors X and IX for phosphatidylserine binding sites was observed.

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Year:  1989        PMID： 2763266     DOI： 10.1016/0049-3848(89)90084-4

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


  2 in total

1.  Seminal vesicle autoantigen, a novel phospholipid-binding protein secreted from luminal epithelium of mouse seminal vesicle, exhibits the ability to suppress mouse sperm motility.

Authors:  Y H Huang; S T Chu; Y H Chen
Journal:  Biochem J       Date:  1999-10-01       Impact factor: 3.857

2.  The association of human coagulation factors VIII, IXa and X with phospholipid vesicles involves both electrostatic and hydrophobic interactions.

Authors:  J S Atkins; P R Ganz
Journal:  Mol Cell Biochem       Date:  1992-05-13       Impact factor: 3.396
  2 in total

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