| Literature DB >> 2763233 |
P T Daniel1, J Holzschuh, P A Berg.
Abstract
A patient developed eosinophilic peripheral pulmonary infiltrates while receiving malaria prophylaxis with sulfadoxine-pyrimethamine (Fansidar). Withdrawal of Fansidar and treatment with corticosteroids led to rapid recovery. No exacerbation occurred after cessation of corticosteroids. Lymphocyte transformation testing gave a positive result in the presence of sulfadoxine but not pyrimethamine. It is concluded that drug hypersensitivity to sulfadoxine was the cause of the eosinophilic pneumonia in this patient.Entities:
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Year: 1989 PMID: 2763233 PMCID: PMC461805 DOI: 10.1136/thx.44.4.307
Source DB: PubMed Journal: Thorax ISSN: 0040-6376 Impact factor: 9.139