Literature DB >> 27632248

An emerging opportunistic infection: fatal astrovirus (VA1/HMO-C) encephalitis in a pediatric stem cell transplant recipient.

Su Han Lum1, Andrew Turner2, Malcolm Guiver2, Denise Bonney1, Timorthy Martland3, Emma Davies2, Melanie Newbould4, Julianne Brown5, Sofia Morfopoulou6, Judith Breuer6, Robert Wynn1.   

Abstract

Neuroinvasive astrovirus (VA1-HMO-C) is an emerging life-threatening infection in immunocompromised hosts. We describe an 8-month-old child who died of VA1/HMO-C encephalitis following bone marrow transplantation. The diagnosis was only made post-mortem using RNA deep sequencing of the brain. Repeat analysis of the post-mortem brain tissue using polymerase chain reaction specific primers for VA1/HMO-C was positive. Astrovirus VA1/HMO-C should be included in the evaluation of patients with similar encephalitis.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  zzm321990BMTzzm321990; astrovirus VA1-HMO-C; deep brain sequencing; unexplained encephalitis

Mesh：

Substances：

Year:  2016        PMID： 27632248     DOI： 10.1111/tid.12607

Source DB:  PubMed          Journal:  Transpl Infect Dis        ISSN： 1398-2273            Impact factor:   2.228


  35 in total

1.  Propagation of Astrovirus VA1, a Neurotropic Human Astrovirus, in Cell Culture.

Authors:  Andrew B Janowski; Irma K Bauer; Lori R Holtz; David Wang
Journal:  J Virol       Date:  2017-09-12       Impact factor: 5.103

Review 2.  Nonsuppurative (Aseptic) Meningoencephalomyelitis Associated with Neurovirulent Astrovirus Infections in Humans and Animals.

Authors:  Gábor Reuter; Péter Pankovics; Ákos Boros
Journal:  Clin Microbiol Rev       Date:  2018-08-29       Impact factor: 26.132

3.  Infection and Propagation of Astrovirus VA1 in Cell Culture.

Authors:  Andrew B Janowski; David Wang
Journal:  Curr Protoc Microbiol       Date:  2018-11-16

4.  Human Astrovirus MLB Replication In Vitro: Persistence in Extraintestinal Cell Lines.

Authors:  Diem-Lan Vu; Albert Bosch; Rosa M Pintó; Enric Ribes; Susana Guix
Journal:  J Virol       Date:  2019-06-14       Impact factor: 5.103

5.  Epidemiology and Genetic Characterization of Classical Human Astrovirus Infection in Shanghai, 2015-2016.

Authors:  Limeng Wu; Zheng Teng; Qingneng Lin; Jing Liu; Huanyu Wu; Xiaozhou Kuang; Xiaoqing Cui; Wei Wang; Xiaoxian Cui; Zheng-An Yuan; Xi Zhang; Youhua Xie
Journal:  Front Microbiol       Date:  2020-09-25       Impact factor: 5.640

6.  Antiviral activity of ribavirin and favipiravir against human astroviruses.

Authors:  Andrew B Janowski; Holly Dudley; David Wang
Journal:  J Clin Virol       Date:  2019-12-17       Impact factor: 3.168

Review 7.  Beyond the Gastrointestinal Tract: The Emerging and Diverse Tissue Tropisms of Astroviruses.

Authors:  Andrew B Janowski
Journal:  Viruses       Date:  2021-04-22       Impact factor: 5.048

8.  Serendipitous Discovery of a Novel Murine Astrovirus Contaminating a Murine Helper T-cell Line and Incapable of Infecting Highly Immunodeficient Mice.

Authors:  Rodolfo J Ricart Arbona; Sean Kelly; Chuanwu Wang; Rajeev K Dhawan; Kenneth S Henderson; William R Shek; Simon H Williams; Eda Altan; Eric Delwart; Felix Wolf; Neil S Lipman
Journal:  Comp Med       Date:  2020-07-16       Impact factor: 0.982

Review 9.  Structural Insights into the Human Astrovirus Capsid.

Authors:  Matthew Ykema; Yizhi J Tao
Journal:  Viruses       Date:  2021-05-01       Impact factor: 5.048

10.  Presence and Diversity of Different Enteric Viruses in Wild Norway Rats (Rattus norvegicus).

Authors:  Sandra Niendorf; Dominik Harms; Katja F Hellendahl; Elisa Heuser; Sindy Böttcher; C-Thomas Bock; Rainer G Ulrich
Journal:  Viruses       Date:  2021-05-26       Impact factor: 5.048
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