Literature DB >> 27631407

Foetal surgery and using in utero therapies to reduce the degree of disability after birth. Could it be morally defensible or even morally required?

Constantinos Kanaris1,2.   

Abstract

In 2008 the Human Fertilisation and Embryology Act amendments made deliberately choosing to bring disability into the world, using assisted reproduction, a criminal offence. This paper considers whether the legal prohibition above, should influence other policy areas concerning the welfare of future children such as new possibilities presented by foetal surgery and in utero gene therapy. If we have legal duties to avoid disability in one context should this influence our avoidance of disability in this other context? This paper investigates whether the State might have a stake in wider promotion of practices to reduce the degree of disability in foetuses that will come to exist (as opposed to those that will be aborted). Not selecting for disability does not affect the welfare of any future individual, whereas treating in utero abnormalities can optimize the eventual child's welfare; antenatal interventions stand to improve clinical outcomes and welfare should that specific child be born. I explore why the State may want to intervene in the antenatal setting and to what extent, if at all; the State should implement these technologies. I argue that if the State is justified in intervening to outlaw the choosing to create disabled lives using assisted reproductive techniques, it is also justified in putting pressure on prospective parents to accept therapies in utero to help their child be born less disabled. However, I qualify this with the argument that the State is not justified in using force or the criminal law in this situation during pregnancy.

Entities:  

Keywords:  Advanced reproductive technologies; Disability; Disability rights; Foetal rights; Foetal surgery; Foetal therapy; Genetic screening; Genetics; Human enhancement; In utero gene therapy; Parental; Pregnancy; Public healthcare policy; Responsibility

Mesh:

Year:  2017        PMID: 27631407     DOI: 10.1007/s11019-016-9727-0

Source DB:  PubMed          Journal:  Med Health Care Philos        ISSN: 1386-7423


  56 in total

1.  Revision of the ICIDH Severity of Disabilities Scale by data linking and item response theory.

Authors:  S van Buuren; M Hopman-Rock
Journal:  Stat Med       Date:  2001-04-15       Impact factor: 2.373

2.  Competent adult (pregnant woman): forced treatment and Mental Health Act -- St. George's Healthcare N.H.S. Trust v. S; R. v. Collins and others, ex parte S.

Authors:  Andrew Grubb
Journal:  Med Law Rev       Date:  1998       Impact factor: 1.267

Review 3.  The hopes and fears of in utero gene therapy for genetic disease--a review.

Authors:  C Coutelle; M Themis; S Waddington; L Gregory; M Nivsarkar; S Buckley; T Cook; C Rodeck; D Peebles; A David
Journal:  Placenta       Date:  2003-10       Impact factor: 3.481

4.  The influence of maternal passive and light active smoking on intrauterine growth and body composition of the newborn.

Authors:  A Luciano; M Bolognani; P Biondani; C Ghizzi; G Zoppi; E Signori
Journal:  Eur J Clin Nutr       Date:  1998-10       Impact factor: 4.016

Review 5.  Current status of thalassemia and the sickle cell syndromes in Greece.

Authors:  D Loukopoulos
Journal:  Semin Hematol       Date:  1996-01       Impact factor: 3.851

Review 6.  The CleanYourHandsCampaign: critiquing policy and evidence base.

Authors:  D J Gould; J Hewitt-Taylor; N S Drey; J Gammon; J Chudleigh; J R Weinberg
Journal:  J Hosp Infect       Date:  2006-12-14       Impact factor: 3.926

7.  "Primum non nocere" and the principle of non-maleficence.

Authors:  R Gillon
Journal:  Br Med J (Clin Res Ed)       Date:  1985-07-13

8.  Surgical treatment of lumbar stenosis in achondroplasia.

Authors:  Ralph T W Thomeer; J Marc C van Dijk
Journal:  J Neurosurg       Date:  2002-04       Impact factor: 5.115

9.  A randomized trial of prenatal versus postnatal repair of myelomeningocele.

Authors:  N Scott Adzick; Elizabeth A Thom; Catherine Y Spong; John W Brock; Pamela K Burrows; Mark P Johnson; Lori J Howell; Jody A Farrell; Mary E Dabrowiak; Leslie N Sutton; Nalin Gupta; Noel B Tulipan; Mary E D'Alton; Diana L Farmer
Journal:  N Engl J Med       Date:  2011-02-09       Impact factor: 91.245

10.  Routine antenatal HIV testing: the responses and perceptions of pregnant women and the viability of informed consent. A qualitative study.

Authors:  Paquita de Zulueta; Mary Boulton
Journal:  J Med Ethics       Date:  2007-06       Impact factor: 2.903

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