Literature DB >> 27630938

Mediastinal Mass with Hyper-eosinophilia in a Young Boy -A Diagnostic Dilemma.

Abdul Shahid Poovathum Parambil1, Shruti Prem2, Priya Mary Jacob3, Rekha Appukuttan Nair4.   

Abstract

Mediastinal masses in children comprises of a heterogeneous group of tumours. In such cases, biopsy and histological analysis are mandatory for planning of treatment. We have reported an unusual aetiology for a mediastinal mass in a young boy presenting with features of Superior Vena Caval Obstruction (SVCO) who also had marked blood and marrow eosinophilia mimicking Chronic Eosinophilic Leukaemia (CEL). We have also discussed the differential diagnoses of mediastinal tumours with hyper-eosinophilia and possible therapeutic implications.

Entities:  

Keywords:  Chest mass; Histiocytosis; Lymphadenopathy; Mediastinal tumour; Superior Vena Caval Obstruction

Year:  2016        PMID: 27630938      PMCID: PMC5020259          DOI: 10.7860/JCDR/2016/19615.8202

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  12 in total

1.  Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB or FGFR1.

Authors:  Barbara J Bain
Journal:  Haematologica       Date:  2010-05       Impact factor: 9.941

2.  Langerhans cell histiocytosis as differential diagnosis of a mediastinal tumor.

Authors:  René Fahrner; Beatrix Hoksch; Mathias Gugger; Ralph Alexander Schmid
Journal:  Eur J Cardiothorac Surg       Date:  2008-02-01       Impact factor: 4.191

Review 3.  Langerhans cell histiocytosis.

Authors:  K Windebank; V Nanduri
Journal:  Arch Dis Child       Date:  2009-05-19       Impact factor: 3.791

4.  How I treat Langerhans cell histiocytosis.

Authors:  Carl E Allen; Stephan Ladisch; Kenneth L McClain
Journal:  Blood       Date:  2015-03-31       Impact factor: 22.113

Review 5.  Chronic eosinophilic leukaemia with FIP1L1-PDGFRA fusion and T6741 mutation that evolved from Langerhans cell histiocytosis with eosinophilia after chemotherapy.

Authors:  Hiroaki Ohnishi; Koji Kandabashi; Yoshiharu Maeda; Machiko Kawamura; Takashi Watanabe
Journal:  Br J Haematol       Date:  2006-09       Impact factor: 6.998

6.  Localized thymic Langerhans' cell histiocytosis and its relationship with myasthenia gravis. Immunohistochemical, ultrastructural, and cytometric studies.

Authors:  M Z Gilcrease; B Rajan; M L Ostrowski; I Ramzy; M R Schwartz
Journal:  Arch Pathol Lab Med       Date:  1997-02       Impact factor: 5.534

Review 7.  Association of Langerhans cell histiocytosis with malignant neoplasms.

Authors:  R M Egeler; J P Neglia; D M Puccetti; C A Brennan; M E Nesbit
Journal:  Cancer       Date:  1993-02-01       Impact factor: 6.860

Review 8.  A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.

Authors:  R C Inhorn; J C Aster; S A Roach; C A Slapak; R Soiffer; R Tantravahi; R M Stone
Journal:  Blood       Date:  1995-04-01       Impact factor: 22.113

Review 9.  Langerhans cell histiocytosis involving the thymus. A case report and review of the literature.

Authors:  Benjamin H Lee; Suzanne George; Jeffery L Kutok
Journal:  Arch Pathol Lab Med       Date:  2003-07       Impact factor: 5.534

10.  Langerhans cell (eosinophilic) granulomatosis. A clinicopathologic study encompassing 50 years.

Authors:  P H Lieberman; C R Jones; R M Steinman; R A Erlandson; J Smith; T Gee; A Huvos; P Garin-Chesa; D A Filippa; C Urmacher; M D Gangi; M Sperber
Journal:  Am J Surg Pathol       Date:  1996-05       Impact factor: 6.394

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