Vinayak Madhu1, Arun Shirali2, Priyanka Niwas Pawaskar3, Deepak Madi2, Nithyananda Chowta4, John Thomas Ramapuram5. 1. Junior Resident, Department of Medicine, Kasturba Medical College, Manipal University , Mangalore, India . 2. Associate Professor, Department of Medicine, Kasturba Medical College, Manipal University , Mangalore, India . 3. Assistant Professor, Department of Physiology, Kanachur Institute of Medical Sciences , Mangalore, India . 4. Additional Professor, Department of Medicine, Kasturba Medical College, Manipal University , Mangalore, India . 5. Professor, Department of Medicine, Kasturba Medical College, Mangalore, Manipal University , Mangalore, India .
Abstract
INTRODUCTION: Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results. AIM: To evaluate effects of mastication on postprandial blood glucose levels. MATERIALS AND METHODS: We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in prospective interventional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups. RESULTS: In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25± 7.82 mg/dl on routine mastication vs 119.74±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07±22.37 mg/dl vs. 243.55±22.87 mg/dl). CONCLUSION: In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.
INTRODUCTION: Mastication has potential to affect postprandial blood glucose levels by affecting cephalic phase of insulin release. However, limited number of studies done in this regard has yielded conflicting results. AIM: To evaluate effects of mastication on postprandial blood glucose levels. MATERIALS AND METHODS: We compared routine and thorough mastication in 2 separate groups: dysglycaemic (prediabetics and diabetics) and normoglycaemic in prospective interventional study. Blood glucose levels were measured pre-prandial and postprandial (after 2 hours) on separate days after routine and thorough mastication in both groups. RESULTS: In normoglycaemic group, thorough mastication significantly reduced postprandial blood glucose levels at 2 hours (128.25± 7.82 mg/dl on routine mastication vs 119.74±9.08 mg/dl on thorough mastication, p<0.05). Comparatively, in dysglycaemic group, thorough mastication had little effect on postprandial blood glucose levels at 2 hours (244.07±22.37 mg/dl vs. 243.55±22.87 mg/dl). CONCLUSION: In normoglycaemic group, postprandial blood glucose concentration upon thorough mastication was significantly lower, due to early-phase insulin secretion. This simple lifestyle modification of thorough mastication can be a useful preventive measure against diabetes in people with a strong family history and other risk factors for diabetes who have not yet developed diabetes or prediabetes.
Entities:
Keywords:
Diabetics; Plasma glucose levels; Pre-diabetics; Rate of chewing
Authors: N W Read; I M Welch; C J Austen; C Barnish; C E Bartlett; A J Baxter; G Brown; M E Compton; K E Hume; I Storie Journal: Br J Nutr Date: 1986-01 Impact factor: 3.718