Literature DB >> 27630876

Endogenous Panophthalmitis in a case of Multiple Myeloma and Diabetes Mellitus.

Madhurima K Nayak1, Neha Singh2.   

Abstract

Multiple myeloma cripples the human body in many ways, one of them being decreased immunity. Infections occurring spontaneously can increase the morbidity. We report a case of an elderly lady with multiple myeloma on treatment and uncontrolled diabetes, who developed loss of vision, swelling and redness of left eye of 4 days duration. There was no history of injury or entry of a foreign body. She also had left arm cellulitis. Ocular examination revealed visual acuity of 6/36 in right eye and no perception of light in left eye. Anterior segment of the right eye was insignificant while the left eye showed features suggestive of panophthalmitis. B scan revealed choroidal detachment and confirmed panophthalmitis. She underwent evisceration of the left eye. The cause of spontaneous infections is an immunocompromised state due to multiple myeloma and uncontrolled diabetes. This case report highlights the propensity of multiple myeloma to cause infections of the eye debilitating enough to cause severe visual morbidity.

Entities:  

Keywords:  B Scan; Evisceration; Perception of light negative; Sloughed cornea

Year:  2016        PMID: 27630876      PMCID: PMC5020220          DOI: 10.7860/JCDR/2016/18699.8164

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

Review 1.  Hyperviscosity syndrome in plasma cell dyscrasias.

Authors:  Jayesh Mehta; Seema Singhal
Journal:  Semin Thromb Hemost       Date:  2003-10       Impact factor: 4.180

2.  Sudden loss of vision: Purtscher retinopathy in multiple myeloma.

Authors:  Amit Nautiyal; Guillermo Amescua; Angus Jameson; Joel F Gradowski; Feiyu Hong; Bernard Doft
Journal:  CMAJ       Date:  2009-11-09       Impact factor: 8.262

3.  18F-fluorodeoxyglucose positron emission tomography contributes to the diagnosis and management of infections in patients with multiple myeloma: a study of 165 infectious episodes.

Authors:  T Mahfouz; M H Miceli; F Saghafifar; S Stroud; L Jones-Jackson; R Walker; M L Grazziutti; G Purnell; A Fassas; G Tricot; B Barlogie; E Anaissie
Journal:  J Clin Oncol       Date:  2005-10-03       Impact factor: 44.544

4.  Bilateral eyelid ecchymoses and corneal crystals: an unusual presentation of multiple myeloma.

Authors:  Debra A Goldstein; Miriam T Schteingart; Andrea D Birnbaum; Howard H Tessler
Journal:  Cornea       Date:  2005-08       Impact factor: 2.651

5.  Ocular findings in multiple myeloma. A report of two cases.

Authors:  T R Baker; W H Spencer
Journal:  Arch Ophthalmol       Date:  1974-02

6.  Recurrent bilateral subconjunctival hemorrhage as an initial presentation of multiple myeloma.

Authors:  Anthony F Felipe; Jennifer M Nottage; Christopher J Rapuano
Journal:  Oman J Ophthalmol       Date:  2012-05

7.  ESBL E. coli Urosepsis Resulting in Endogenous Panophthalmitis Requiring Evisceration of the Eye in a Diabetic Patient.

Authors:  Tejaswini Arunachala Murthy; Pradeep Rangappa; Sangeetha Rao; Karthik Rao
Journal:  Case Rep Infect Dis       Date:  2015-08-17
  7 in total

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