Linlin Cui1,2,3,4, Lei Li1,2,3,4,5, Eli Y Adashi6, Zi-Jiang Chen7,8,9,10,11,12. 1. Center for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, Jinan, China. 2. Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China. 3. Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China. 4. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China. 5. Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana, USA. 6. The Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA. 7. Center for Reproductive Medicine, Provincial Hospital Affiliated to Shandong University, Jinan, China. chenzijiang@hotmail.com. 8. Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China. chenzijiang@hotmail.com. 9. Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China. chenzijiang@hotmail.com. 10. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China. chenzijiang@hotmail.com. 11. Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. chenzijiang@hotmail.com. 12. Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, China. chenzijiang@hotmail.com.