Literature DB >> 27626794

Should We Always Defer Treatment of Kidney Disease When There Is Extensive Interstitial Fibrosis on Biopsy?

Musab S Hommos1, Andrew D Rule.   

Abstract

Severity of interstitial fibrosis and tubular atrophy (IFTA) seen on kidney biopsy has been used by nephrologist as prognostic marker of kidney disease. While IFTA is a very strong predictor of kidney failure, some patients with severe fibrosis will still not progress to kidney failure within 5 years. Treatment of underlying kidney disease in select patients with severe IFTA should be considered when risks of treatment are reasonable despite the low potential for benefit.
© 2016 S. Karger AG, Basel.

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Year:  2016        PMID： 27626794      PMCID： PMC5069176          DOI： 10.1159/000449513

Source DB:  PubMed          Journal:  Am J Nephrol        ISSN： 0250-8095            Impact factor:   3.754


  5 in total

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Journal:  Am J Kidney Dis       Date:  2016-02-06       Impact factor: 8.860

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  1 in total

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