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Literature DB >> 27626769

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus.

Quanyin Hu^1,2, Chenggen Qian^1,2,3, Wujin Sun^1,2, Jinqiang Wang^1,2, Zhaowei Chen^1,2, Hunter N Bomba^1,2, Hongliang Xin^1,2,4, Qundong Shen³, Zhen Gu^1,2,5.

Abstract

A platelet-membrane-coated biomimetic nanocarrier, which can sequentially target the bone microenvironment and myeloma cells to enhance the drug availability at the myeloma site and decrease off-target effects, is developed for inhibiting multiple myeloma growth and simultaneously eradicating thrombus complication.

Entities: CellLine Chemical Disease Gene Species

Keywords: biomimetics; drug delivery; multiple myeloma; platelets; thrombus

Mesh：

Substances：
Drug Carriers

Year: 2016 PMID： 27626769 PMCID： PMC5283718 DOI： 10.1002/adma.201603463

Source DB: PubMed Journal: Adv Mater ISSN： 0935-9648 Impact factor: 30.849

39 in total

Review 1. Platelets in atherothrombosis.

Authors: Zaverio M Ruggeri
Journal: Nat Med Date: 2002-11 Impact factor: 53.440

2. Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform.

Authors: Che-Ming J Hu; Li Zhang; Santosh Aryal; Connie Cheung; Ronnie H Fang; Liangfang Zhang
Journal: Proc Natl Acad Sci U S A Date: 2011-06-20 Impact factor: 11.205

3. Targeted drug delivery to circulating tumor cells via platelet membrane-functionalized particles.

Authors: Jiahe Li; Yiwei Ai; Lihua Wang; Pengcheng Bu; Charles C Sharkey; Qianhui Wu; Brittany Wun; Sweta Roy; Xiling Shen; Michael R King
Journal: Biomaterials Date: 2015-10-21 Impact factor: 12.479

4. CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells.

Authors: M Van Driel; U Günthert; A C van Kessel; P Joling; R Stauder; H M Lokhorst; A C Bloem
Journal: Leukemia Date: 2002-01 Impact factor: 11.528

Review 5. Latest advances and current challenges in the treatment of multiple myeloma.

Authors: Anuj Mahindra; Jacob Laubach; Noopur Raje; Nikhil Munshi; Paul G Richardson; Kenneth Anderson
Journal: Nat Rev Clin Oncol Date: 2012-02-21 Impact factor: 66.675

6. Engineered nanomedicine for myeloma and bone microenvironment targeting.

Authors: Archana Swami; Michaela R Reagan; Pamela Basto; Yuji Mishima; Nazila Kamaly; Siobhan Glavey; Sufeng Zhang; Michele Moschetta; Dushanth Seevaratnam; Yong Zhang; Jinhe Liu; Masoumeh Memarzadeh; Jun Wu; Salomon Manier; Jinjun Shi; Nicolas Bertrand; Zhi Ning Lu; Kenichi Nagano; Roland Baron; Antonio Sacco; Aldo M Roccaro; Omid C Farokhzad; Irene M Ghobrial
Journal: Proc Natl Acad Sci U S A Date: 2014-06-30 Impact factor: 11.205

7. Curing myeloma at last: defining criteria and providing the evidence.

Authors: Bart Barlogie; Alan Mitchell; Frits van Rhee; Joshua Epstein; Gareth J Morgan; John Crowley
Journal: Blood Date: 2014-10-07 Impact factor: 22.113

8. Thrombosis is associated with inferior survival in multiple myeloma.

Authors: Sigurdur Y Kristinsson; Ruth M Pfeiffer; Magnus Björkholm; Sam Schulman; Ola Landgren
Journal: Haematologica Date: 2012-04-17 Impact factor: 9.941

Review 9. Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy.

Authors: Robert C Kane; Peter F Bross; Ann T Farrell; Richard Pazdur
Journal: Oncologist Date: 2003

10. Identification of an inhibitor of tissue-type plasminogen activator-mediated fibrinolysis in human neutrophils. A role for defensin.

Authors: A A Higazi; I I Barghouti; R Abu-Much
Journal: J Biol Chem Date: 1995-04-21 Impact factor: 5.157

39 in total

Review 1. Engineering biological interactions on the nanoscale.

Authors: Yao Jiang; Sanam Chekuri; Ronnie H Fang; Liangfang Zhang
Journal: Curr Opin Biotechnol Date: 2018-11-01 Impact factor: 9.740

2. Synthetic beta cells for fusion-mediated dynamic insulin secretion.

Authors: Zhaowei Chen; Jinqiang Wang; Wujin Sun; Edikan Archibong; Anna R Kahkoska; Xudong Zhang; Yue Lu; Frances S Ligler; John B Buse; Zhen Gu
Journal: Nat Chem Biol Date: 2017-10-30 Impact factor: 15.040

3. Erythrocyte-Platelet Hybrid Membrane Coating for Enhanced Nanoparticle Functionalization.

Authors: Diana Dehaini; Xiaoli Wei; Ronnie H Fang; Sarah Masson; Pavimol Angsantikul; Brian T Luk; Yue Zhang; Man Ying; Yao Jiang; Ashley V Kroll; Weiwei Gao; Liangfang Zhang
Journal: Adv Mater Date: 2017-02-15 Impact factor: 30.849

Review 4. Biomimetic nanoparticle technology for cardiovascular disease detection and treatment.

Authors: Joon Ho Park; Diana Dehaini; Jiarong Zhou; Maya Holay; Ronnie H Fang; Liangfang Zhang
Journal: Nanoscale Horiz Date: 2019-06-28 Impact factor: 10.989

5. Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury.

Authors: Teng Su; Ke Huang; Hong Ma; Hongxia Liang; Phuong-Uyen Dinh; Justin Chen; Deliang Shen; Tyler A Allen; Li Qiao; Zhenhua Li; Shiqi Hu; Jhon Cores; Brianna N Frame; Ashlyn T Young; Qi Yin; Jiandong Liu; Li Qian; Thomas G Caranasos; Yevgeny Brudno; Frances S Ligler; Ke Cheng
Journal: Adv Funct Mater Date: 2018-11-13 Impact factor: 18.808