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Literature DB >> 2762604

A stochastic two-stage model for cancer risk assessment. II. The number and size of premalignant clones.

Abstract

Mathematical expressions are derived, under different dosing patterns, for the number and size of premalignant clones within the framework of a two-mutation model for carcinogenesis, which has previously been shown to be consistent with a large body of epidemiologic and experimental data.

Entities: Disease

Mesh：

Year: 1989 PMID： 2762604 DOI： 10.1111/j.1539-6924.1989.tb01238.x

Source DB: PubMed Journal: Risk Anal ISSN： 0272-4332 Impact factor: 4.000

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Cited

11 in total

1. Evaluation of screening strategies for pre-malignant lesions using a biomathematical approach.

Authors: Jihyoun Jeon; Rafael Meza; Suresh H Moolgavkar; E Georg Luebeck
Journal: Math Biosci Date: 2008-02-26 Impact factor: 2.144

2. Multiscale estimation of cell kinetics.

Authors: Larry W Jean; Martin T Suchorolski; Jihyoun Jeon; E Georg Luebeck
Journal: Comput Math Methods Med Date: 2010-09 Impact factor: 2.238

3. Quantifying the Dynamics of Field Cancerization in Tobacco-Related Head and Neck Cancer: A Multiscale Modeling Approach.

Authors: Marc D Ryser; Walter T Lee; Neal E Ready; Kevin Z Leder; Jasmine Foo
Journal: Cancer Res Date: 2016-10-20 Impact factor: 12.701

Review 9. Cell proliferation and carcinogenesis models: general principles with illustrations from the rodent liver system.

Authors: S H Moolgavkar
Journal: Environ Health Perspect Date: 1993-12 Impact factor: 9.031

10. Parameter estimation for multistage clonal expansion models from cancer incidence data: A practical identifiability analysis.

Authors: Andrew F Brouwer; Rafael Meza; Marisa C Eisenberg
Journal: PLoS Comput Biol Date: 2017-03-13 Impact factor: 4.475

A stochastic two-stage model for cancer risk assessment. II. The number and size of premalignant clones.

1. Evaluation of screening strategies for pre-malignant lesions using a biomathematical approach.

2. Multiscale estimation of cell kinetics.

3. Quantifying the Dynamics of Field Cancerization in Tobacco-Related Head and Neck Cancer: A Multiscale Modeling Approach.

4. A Systematic Approach to Determining the Identifiability of Multistage Carcinogenesis Models.

Review 5. Systems biological and mechanistic modelling of radiation-induced cancer.

6. Number and size distribution of colorectal adenomas under the multistage clonal expansion model of cancer.

7. Biological bases for cancer dose-response extrapolation procedures.

8. Models for analyzing data in initiation-promotion studies.

Review 9. Cell proliferation and carcinogenesis models: general principles with illustrations from the rodent liver system.

10. Parameter estimation for multistage clonal expansion models from cancer incidence data: A practical identifiability analysis.