| Literature DB >> 27624903 |
A Gliese1, C-J Busch1, R Knecht2.
Abstract
At the annual meeting of the American Society of Clinical Oncology (ASCO) 2016, results of current trials dealing with primary therapy for head and neck squamous cell carcinoma (HNSCC) were presented. Current trials investigate in particular therapy regimens for the treatment of locally advanced HNSCC. Concomitant chemoradiotherapy (CRT) remains the standard therapy approach. Current trials focus on sequential chemoradiation with modifications in induction chemotherapy (ICT) or the subsequent CRT schedule. Studies investigating the combination of targeted therapy with the epidermal growth factor receptor (EGFR) antibody cetuximab and concomitant, sequential, or adjuvant therapy were presented. The most important trials are summarized in this article.Entities:
Keywords: EGF receptor; Induction chemotherapy; Radiochemotherapy; Squamous cell carcinoma of the head and neck; Targeted molecular therapy
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Year: 2016 PMID: 27624903 DOI: 10.1007/s00106-016-0243-6
Source DB: PubMed Journal: HNO ISSN: 0017-6192 Impact factor: 1.284