Literature DB >> 27624854

Two-dose seasonal influenza vaccine coverage and timeliness among children aged 6 months through 3 years: An evidence from the 2010-11 to the 2014-15 seasons in Zhejiang province, east China.

Yu Hu1, Yaping Chen2, Bing Zhang3.   

Abstract

OBJECTIVE: To evaluate the coverage and timeliness of seasonal influenza vaccine vaccination (SIV) among children aged 6 months to 3 years from the 2010-11 through the 2014-15 seasons.
METHODS: Children registered in Zhejiang Provincial Immunization Information System (ZJIIS) and needed 2 seasonal influenza vaccine doses in a given season from 2010-11 to 2014-15 were enrolled. Socio-economic information and SIV records of target children were extracted from ZJIIS on 1 January 2016. Any (≥1 dose) and full (2 doses) vaccination coverage by December 1 and March 31 as well as interval between 2 doses were calculated. Trends of coverage over time and determinants on fully vaccination coverage and interval between 2 doses were assessed.
RESULTS: Full SIV overage by Mar 31 increased from the 2010-11 to the 2014-15 seasons (2.60% vs 2.92%). Less than 1% of children received 2 doses by December 1. The interval between 2 doses among fully vaccinated children decreased over time (2010-11: 68.32 days; 2014-15: 49.51 days; p < 0.05). Age, socio-economic development level of resident areas were inversely associated with full vaccination coverage and resident children had a significantly higher full vaccination coverage. Younger age, resident children, receiving vaccination from higher service frequency clinics and clinics with morning and afternoon sessions were positive determinants of a shorter interval between 2 doses.
CONCLUSION: Majority of children aged 6 months to 3 years remained at risk of incomplete and delayed SIV. The importance of the 2-dose SIV recommendation needs to be emphasized and effective interventions needs to be implemented to improve the completeness and the timeliness of SIV.

Entities:  

Keywords:  children; immunization information system; seasonal influenza vaccine; timeliness; vaccination coverage

Mesh:

Substances:

Year:  2016        PMID: 27624854      PMCID: PMC5287310          DOI: 10.1080/21645515.2016.1225640

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN: 2164-5515            Impact factor:   3.452


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