Literature DB >> 27624178

High-load preconditioning of human soft tissue hamstring grafts: An in vitro biomechanical analysis.

W Charles Lockwood1, Daniel Cole Marchetti1, Kimi D Dahl1, Jacob D Mikula1, Brady T Williams1, Matthew M Kheir1, Travis Lee Turnbull1, Robert F LaPrade2,3.   

Abstract

PURPOSE: In order to minimize viscoelastic elongation of ACL reconstruction grafts, preconditioning protocols have been employed in clinical practice prior to final graft fixation. The purpose of this study was to evaluate two separate high-load static preconditioning protocols of double-looped semitendinosus-gracilis grafts and compare these results to both a current clinical protocol and a control group with no preconditioning protocol applied. It was hypothesized that a high-load, static preconditioning protocol would minimize graft elongation during a simulated progressive early rehabilitation compared to both the "89 N" clinical protocol and control groups.
METHODS: Grafts were randomly allocated into four preconditioning study groups: (1) control (no preconditioning), (2) clinical protocol (89 N for 15 min), (3) high-load, short duration (600 N for 20 s), and (4) high-load, long duration (600 N for 15 min). After preconditioning, grafts were cyclically loaded between 10 and 400 N at 0.5 Hz for 450 cycles to simulate early postoperative rehabilitation. Graft displacement (elongation) was recorded during both preconditioning and cyclic loading.
RESULTS: Increased preconditioning load magnitude and duration significantly reduced graft elongation during cyclic loading (p < 0.05) which corresponded to an inverse relationship with increased elongation during preconditioning. The "600 N for 15 min" protocol resulted in significantly less elongation during simulated early rehabilitation than both the control group and the "89 N for 15 min" protocol (p < 0.001, p < 0.05).
CONCLUSIONS: Graft elongation during simulated early rehabilitation was significantly reduced by a high-load preconditioning protocol applied for an extended period of time compared to a current common clinical protocol and grafts that were not preconditioned. In addition, the amount of elongation during simulated early rehabilitation was similar between grafts preconditioned using the current clinical practice protocol and the high-load/short-duration protocol, implying that the latter could potentially induce the same viscoelastic changes in soft tissue grafts as the current clinical practice. The "600 N for 20 s" preconditioning protocol may provide similar postoperative results as the clinical protocol, "89 N for 15 min", and also reduce or maintain operative time. A high-load preconditioning protocol that reduces graft elongation may benefit patients undergoing ACL reconstruction, especially for cases of failed primary reconstruction, genu recurvatum, and increased tibial slope, where maintaining graft length is imperative to restore knee stability.

Entities:  

Keywords:  ACL reconstruction; Gracilis; Hamstring grafts; Knee joint; Preconditioning; Semitendinosus

Mesh:

Year:  2016        PMID: 27624178     DOI: 10.1007/s00167-016-4317-5

Source DB:  PubMed          Journal:  Knee Surg Sports Traumatol Arthrosc        ISSN: 0942-2056            Impact factor:   4.342


  31 in total

Review 1.  Current trends in anterior cruciate ligament reconstruction. Part 1: Biology and biomechanics of reconstruction.

Authors:  F H Fu; C H Bennett; C Lattermann; C B Ma
Journal:  Am J Sports Med       Date:  1999 Nov-Dec       Impact factor: 6.202

Review 2.  Anterior and posterior cruciate ligament reconstruction in the new millennium: a global perspective.

Authors:  C D Harner; F H Fu; J J Irrgang; T M Vogrin
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2001-08-08       Impact factor: 4.342

3.  Lengthening of double-looped tendon graft constructs in three regions after cyclic loading: a study using Roentgen stereophotogrammetric analysis.

Authors:  P J Roos; M L Hull; S M Howell
Journal:  J Orthop Res       Date:  2004-07       Impact factor: 3.494

4.  Effects of graft pretensioning in anterior cruciate ligament reconstruction.

Authors:  Claude Guillard; Francois Lintz; Guillaume Anthony Odri; Denis Vogeli; Fabrice Colin; Sylvie Collon; Daniel Chappard; François Gouin; Henri Robert
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-01-05       Impact factor: 4.342

5.  Viscoelasticity and temperature variations decrease tension and stiffness of hamstring tendon grafts following anterior cruciate ligament reconstruction.

Authors:  William J Ciccone; Derek R Bratton; David M Weinstein; John J Elias
Journal:  J Bone Joint Surg Am       Date:  2006-05       Impact factor: 5.284

6.  High-load preconditioning of soft tissue grafts: an in vitro biomechanical bovine tendon model.

Authors:  Jeffrey R Jaglowski; Brady T Williams; Travis Lee Turnbull; Robert F LaPrade; Coen A Wijdicks
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-11-08       Impact factor: 4.342

7.  Effect of Different Preconditioning Protocols on Anterior Knee Laxity After ACL Reconstruction with Four Commonly Used Grafts.

Authors:  Daniel V Boguszewski; Nirav B Joshi; Dean Wang; Keith L Markolf; Frank A Petrigliano; David R McAllister
Journal:  J Bone Joint Surg Am       Date:  2015-07-01       Impact factor: 5.284

8.  Lack of consensus regarding pretensioning and preconditioning protocols for soft tissue graft reconstruction of the anterior cruciate ligament.

Authors:  Kyle A Jisa; Brady T Williams; Jeffrey R Jaglowski; Travis Lee Turnbull; Robert F LaPrade; Coen A Wijdicks
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-02-26       Impact factor: 4.342

9.  Femoral cortical suspension devices for soft tissue anterior cruciate ligament reconstruction: a comparative biomechanical study.

Authors:  Benjamin M Petre; Sean D Smith; Kyle S Jansson; Peter-Paul de Meijer; Thomas R Hackett; Robert F LaPrade; Coen A Wijdicks
Journal:  Am J Sports Med       Date:  2012-12-20       Impact factor: 6.202

10.  Anterior cruciate ligament reconstruction with patellar tendon. An ex vivo study of wear-related damage and failure at the femoral tunnel.

Authors:  B K Graf; J Henry; M Rothenberg; R Vanderby
Journal:  Am J Sports Med       Date:  1994 Jan-Feb       Impact factor: 6.202

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  1 in total

1.  Modified Lemaire tenodesis reduces anterior cruciate ligament graft forces during internal tibial torque loading.

Authors:  Raul Mayr; Maximilian Sigloch; Christian Coppola; Romed Hoermann; Alessandra Iltchev; Werner Schmoelz
Journal:  J Exp Orthop       Date:  2022-05-18
  1 in total

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