Literature DB >> 27623948

An alternative effector gene at the type 2 diabetes-associated TCF7L2 locus?

Martijn van de Bunt1,2.   

Abstract

Entities:  

Keywords:  ACSL5; Genetics; Genome-wide association study; TCF7L2; Type 2 diabetes

Mesh：

Substances：

Year:  2016        PMID： 27623948     DOI： 10.1007/s00125-016-4103-4

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


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  14 in total

1.  TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta.

Authors:  Fenghua Yi; Patricia L Brubaker; Tianru Jin
Journal:  J Biol Chem       Date:  2004-11-02       Impact factor: 5.157

2.  Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.

Authors:  Valeriya Lyssenko; Roberto Lupi; Piero Marchetti; Silvia Del Guerra; Marju Orho-Melander; Peter Almgren; Marketa Sjögren; Charlotte Ling; Karl-Fredrik Eriksson; Asa-Linda Lethagen; Rita Mancarella; Göran Berglund; Tiinamaija Tuomi; Peter Nilsson; Stefano Del Prato; Leif Groop
Journal:  J Clin Invest       Date:  2007-08       Impact factor: 14.808

3.  The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5.

Authors:  Qianghua Xia; Alessandra Chesi; Elisabetta Manduchi; Brian T Johnston; Sumei Lu; Michelle E Leonard; Ursula W Parlin; Eric F Rappaport; Peng Huang; Andrew D Wells; Gerd A Blobel; Matthew E Johnson; Struan F A Grant
Journal:  Diabetologia       Date:  2016-08-18       Impact factor: 10.122

4.  FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.

Authors:  Melina Claussnitzer; Simon N Dankel; Kyoung-Han Kim; Gerald Quon; Wouter Meuleman; Christine Haugen; Viktoria Glunk; Isabel S Sousa; Jacqueline L Beaudry; Vijitha Puviindran; Nezar A Abdennur; Jannel Liu; Per-Arne Svensson; Yi-Hsiang Hsu; Daniel J Drucker; Gunnar Mellgren; Chi-Chung Hui; Hans Hauner; Manolis Kellis
Journal:  N Engl J Med       Date:  2015-08-19       Impact factor: 91.245

5.  A map of open chromatin in human pancreatic islets.

Authors:  Kyle J Gaulton; Takao Nammo; Lorenzo Pasquali; Jeremy M Simon; Paul G Giresi; Marie P Fogarty; Tami M Panhuis; Piotr Mieczkowski; Antonio Secchi; Domenico Bosco; Thierry Berney; Eduard Montanya; Karen L Mohlke; Jason D Lieb; Jorge Ferrer
Journal:  Nat Genet       Date:  2010-01-31       Impact factor: 38.330

6.  Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.

Authors:  Sylvia F Boj; Johan H van Es; Meritxell Huch; Vivian S W Li; Anabel José; Pantelis Hatzis; Michal Mokry; Andrea Haegebarth; Maaike van den Born; Pierre Chambon; Peter Voshol; Yuval Dor; Edwin Cuppen; Cristina Fillat; Hans Clevers
Journal:  Cell       Date:  2012-12-21       Impact factor: 41.582

7.  Human genomics. The human transcriptome across tissues and individuals.

Authors:  Marta Melé; Pedro G Ferreira; Ferran Reverter; David S DeLuca; Jean Monlong; Michael Sammeth; Taylor R Young; Jakob M Goldmann; Dmitri D Pervouchine; Timothy J Sullivan; Rory Johnson; Ayellet V Segrè; Sarah Djebali; Anastasia Niarchou; Fred A Wright; Tuuli Lappalainen; Miquel Calvo; Gad Getz; Emmanouil T Dermitzakis; Kristin G Ardlie; Roderic Guigó
Journal:  Science       Date:  2015-05-08       Impact factor: 47.728

8.  Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.

Authors:  Martijn van de Bunt; Jocelyn E Manning Fox; Xiaoqing Dai; Amy Barrett; Caleb Grey; Lei Li; Amanda J Bennett; Paul R Johnson; Raymond V Rajotte; Kyle J Gaulton; Emmanouil T Dermitzakis; Patrick E MacDonald; Mark I McCarthy; Anna L Gloyn
Journal:  PLoS Genet       Date:  2015-12-01       Impact factor: 5.917

9.  Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption.

Authors:  Thomas A Bowman; Kayleigh R O'Keeffe; Theresa D'Aquila; Qing Wu Yan; John D Griffin; Elizabeth A Killion; Deanna M Salter; Douglas G Mashek; Kimberly K Buhman; Andrew S Greenberg
Journal:  Mol Metab       Date:  2016-01-11       Impact factor: 7.422

10.  The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.

Authors:  Gautier Koscielny; Gagarine Yaikhom; Vivek Iyer; Terrence F Meehan; Hugh Morgan; Julian Atienza-Herrero; Andrew Blake; Chao-Kung Chen; Richard Easty; Armida Di Fenza; Tanja Fiegel; Mark Grifiths; Alan Horne; Natasha A Karp; Natalja Kurbatova; Jeremy C Mason; Peter Matthews; Darren J Oakley; Asfand Qazi; Jack Regnart; Ahmad Retha; Luis A Santos; Duncan J Sneddon; Jonathan Warren; Henrik Westerberg; Robert J Wilson; David G Melvin; Damian Smedley; Steve D M Brown; Paul Flicek; William C Skarnes; Ann-Marie Mallon; Helen Parkinson
Journal:  Nucleic Acids Res       Date:  2013-11-04       Impact factor: 16.971
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  4 in total

1.  Diabetes-associated genetic variation in TCF7L2 alters pulsatile insulin secretion in humans.

Authors:  Marcello C Laurenti; Chiara Dalla Man; Ron T Varghese; James C Andrews; Robert A Rizza; Aleksey Matveyenko; Giuseppe De Nicolao; Claudio Cobelli; Adrian Vella
Journal:  JCI Insight       Date:  2020-04-09

2.  Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes.

Authors:  Maria J Redondo; Andrea K Steck; Jay Sosenko; Mark Anderson; Peter Antinozzi; Aaron Michels; John M Wentworth; Mark A Atkinson; Alberto Pugliese; Susan Geyer
Journal:  Diabetes Care       Date:  2018-10-01       Impact factor: 19.112

Review 3.  Cystic Fibrosis-Related Diabetes (CFRD): Overview of Associated Genetic Factors.

Authors:  Fernanda Iafusco; Giovanna Maione; Francesco Maria Rosanio; Enza Mozzillo; Adriana Franzese; Nadia Tinto
Journal:  Diagnostics (Basel)       Date:  2021-03-22

4.  TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes.

Authors:  Maria J Redondo; Susan Geyer; Andrea K Steck; Jay Sosenko; Mark Anderson; Peter Antinozzi; Aaron Michels; John Wentworth; Ping Xu; Alberto Pugliese
Journal:  Diabetes Care       Date:  2017-10-12       Impact factor: 19.112
  4 in total

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