| Literature DB >> 27623548 |
Ta-Yuan Whuang1, Wen-Cheng Tsai2, Nan-Fu Chen3, Zhi-Cheng Chen4, Kuan-Hao Tsui5, Zhi-Hong Wen6, Yin-Di Su7, Yu-Chia Chang8, Yu-Hsin Chen9, Mei-Chin Lu1, Lee-Shing Fang10, Jih-Jung Chen11, Tung-Ying Wu12, Yang-Chang Wu13, Ping-Jyun Sung14.
Abstract
Columnaristerol A (1), a rare natural 19-norsterol possessing a 10β-hydroxy group was isolated from the Formosan octocoral Nephthea columnaris, and its structure was elucidated by spectroscopic methods. Sterol 1 was found to be a cytotoxic agent that exhibited in vitro moderate cytotoxic activity against MOLT-4 and SUP-T1 human leukemia-lymphoma cell lines.Entities:
Keywords: 19-Norsterol; Columnaristerol; Cytotoxicity; Nephthea columnaris
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Year: 2016 PMID： 27623548 DOI： 10.1016/j.bmcl.2016.09.007
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823