Literature DB >> 27622618

Successful treatment of hemophagocytic lymphohistiocytosis and disseminated intravascular coagulation secondary to histoplasmosis in a patient with HIV/AIDS.

John Fredy Nieto1, Sandra Milena Gómez, Diana Carolina Moncada, Lina María Serna, Alicia Inés Hidrón.   

Abstract

Haemophagocytic lymphohistiocytosis is an uncommon syndrome that results from an uncontrolled activation of macrophages and lymphocytes resulting in the compromise of multiple organs that is potentially fatal without timely treatment. It can be hereditary or a secondary result of infectious processes, neoplasms or autoimmune conditions. We present the case of a patient with HIV/AIDS who developed hemophagocytic lymphohistiocytosis as well as disseminated intravascular coagulation associated with histoplasmosis and who was successfully treated with amphotericin B, steroids and transitory dialytic support.

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Keywords:  Lymphohistiocytosis; acquired immunodeficiency syndrome; disseminated intravascular coagulation; hemophagocytic; histoplasmosis

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Year:  2016        PMID: 27622618     DOI: 10.7705/biomedica.v36i2.2797

Source DB:  PubMed          Journal:  Biomedica        ISSN: 0120-4157            Impact factor:   0.935


  3 in total

1.  Disseminated Mycobacterium avium-Intracellulare Complex Infection Presenting With Disseminated Intravascular Coagulation in an AIDS Patient.

Authors:  Folusakin Ayoade; James Cotelingam; Andrew Stevenson Joel Chandranesan
Journal:  J Investig Med High Impact Case Rep       Date:  2017-11-14

Review 2.  Histoplasmosis-Associated Hemophagocytic Lymphohistiocytosis: A Review of the Literature.

Authors:  Ra'ed Jabr; Wissam El Atrouni; Heather J Male; Kassem A Hammoud
Journal:  Can J Infect Dis Med Microbiol       Date:  2019-10-01       Impact factor: 2.471

3.  Hemophagocytic Lymphohistiocytosis During HIV Infection in Cayenne Hospital 2012-2015: First Think Histoplasmosis.

Authors:  Duc Nguyen; Mathieu Nacher; Loic Epelboin; Alessia Melzani; Magalie Demar; Denis Blanchet; Romain Blaizot; Kinan Drak Alsibai; Philippe Abboud; Félix Djossou; Pierre Couppié; Antoine Adenis
Journal:  Front Cell Infect Microbiol       Date:  2020-09-24       Impact factor: 6.073

  3 in total

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