Health in a fragile state: a five-year review of mortality patterns and trends at Somalia's Banadir Hospital.

BACKGROUND: The recurrent civil conflict in Somalia has impeded progress toward improving health and health care, with lack of data and poor performance of health indicators. This study aimed at making inference about Banadir region by exploring morbidity and mortality trends at Banadir Hospital. This is one of the few functional hospitals during war.
METHODS: A retrospective analysis was conducted with data collected at Banadir Hospital for the period of January 2008-December 2012. The data were aggregated from patient records and summarized on a morbidity and mortality surveillance form with respect to age groups and stratified by sex. The main outcome was the number of patients that died in the hospital. Chi-square tests were used to evaluate the association between sex and hospital mortality.
RESULTS: Conditions of infectious origin were the major presentations at the hospital. The year 2011 recorded the highest number of cases of diarrhea and mortality due to diarrhea. The stillbirth rate declined during the study period from 272 to 48 stillbirths per 1,000 live births by 2012. The sum of total cases that were attended to at the hospital by the end of 2012 was four times the number at the baseline year of the study in 2008; however, the overall mortality rate among those admitted declined between 2008 and 2012.
CONCLUSION: There was reduction in patient mortality at the hospital over the study period. Data from Banadir Hospital are consistent with findings from Banadir region and could give credible public health reflections for the region given the lack of data on a population level.

Background

Somalia, the easternmost nation in the Horn of Africa,1 is classified as a fragile state. The recurrent civil conflict for over 20 years has impeded progress toward improving health care in Somalia.2 Its capital Mogadishu has been a haven for armed gangs, Islamic militants, and pirates, and for more than two decades, the country has been characterized by insecurity and outbreaks of hunger and inadequate access to basic needs and services.3 According to a recent United Nations Population Fund report, Somalia’s population stands at 12.3 million people with 45.6% of its people <15 years of age.4 It is a youthful population, with a growth rate of 2.8%, which is among the highest in the world.5 On average, every woman bears 6.6 children6 and each household in Somalia has a mean of 5.9 persons.4

The current insecurity has undermined the impact of humanitarian assistance in Somalia, a country where half of the population is dependent on health relief and food aid. The government has been unable to implement the rule of law, and external aid including medical supplies constantly faces the threat of diversion.7 The increase and continuous influx of injured people has created conflict of interest for health care resources and prioritization of allocating funds. This precedent has created a gap in birth and death registration. Monitoring of progress in the public health arena has deteriorated, hence the need to provide progressive assessment of health outcomes. Since 2008, health reports and disease surveillance information have been scanty in Somalia. Demographic surveillance and birth and death registration systems have come to a standstill, and this limits tracking of progress of health indicators. Through the Multiple Indicator Cluster Survey, the United Nations International Children’s Fund established a platform to monitor child and maternal indicators; however, this was only possible until 2006.8 There has been a census recently; however, there is no Demographic and Health Surveillance data which are informative about the county’s health indicators.

Banadir region is the most populous among the 18 prewar regions of Somalia. It is mainly urban with a population of 1.6 million people, and it had the highest number of internally displaced persons in the country by 2014.4 Banadir Hospital,9 also known as the only national referral hospital in Somalia, has since its establishment been the center of health care delivery in Mogadishu. The hospital comprises both maternity and pediatric departments where mothers and children are treated, respectively; however its emergency department offers routine medical and surgical services.

In this article, our primary objective was to explore morbidity and mortality patterns of the presenting conditions in the different units at the hospital such that an overview of Somalia can be inferred. We also explore whether sex has an association with these outcomes. Sex is a multidimensional social construct10 and investigation of this precedent would provide an insight into health outcomes for males in a male-dominated community at war. The Gender Inequality Index11 for Somalia is 0.776 (with a maximum of 1, meaning complete inequality), which is the fourth highest position globally,12 and studies have shown that Gender Inequality Index is positively associated with under-5 mortality rates.13 We also highlight the hospital’s performance, gaps in management, and progress made during this study period.

Data and methods

Study design and setting

This study was done as a retrospective analysis of collected hospital data. Banadir Hospital is a teaching hospital located in the Wadajir district of Mogadishu in Somalia. It consists of four main sections: a pediatric section, a maternity section, a laboratory, and a section for general medicine with a bed capacity of 700. The hospital offers medical and surgical services and also voluntary counselling and testing (VCT) for human immunodeficiency virus (HIV), prevention of mother-to-child transmission (PMTCT),14 and the expanded program on immunization (EPI) services.15 Patients are usually admitted through the Out-Patient Department; however, emergencies are received at the Accident and Emergency unit. Surgical services are provided at the medical section. Admission and medicines are free, but laboratory tests and X-ray services are priced. The hospital is mainly funded by nongovernmental organizations, and they equally provide training to staff including doctors, nurses, and nurses’ assistants.

Data collection

Data were collected between January 2008 and December 2012. All patients that were diagnosed and attended to at the hospital were included in the study. Patient consent was not required as this was aggregated data that was anonymous and had no patient identifying information. For 5 years, aggregated data were obtained from patients’ records and it included age (dichotomized as <5 or >5 years), sex, their presenting diagnosis, and outcomes. Diagnoses were made by the doctors who attended to the patients in each unit in accordance with Somalia’s clinical guidelines and also laboratory confirmation. Data completeness were not ascertained; however, data of all patients treated at the hospital were recorded. Annual data were compiled into a report and recorded on a morbidity and surveillance form. This was recorded in Excel files for the 5-year period. Total number of admissions, discharges, and deaths were also compiled for every month.

Data obtained from the maternity ward included numbers of live births and stillbirths, deliveries, and cases of tetanus. Data from the pediatric section and the laboratory were also obtained. Data on mortality were also obtained from death certificates that are issued daily. Patients that died before diagnosis were diagnosed through post mortem done at the hospital by hospital staff, and those that lacked a diagnosis were included in a category of “others”. Information from patients’ files was summarized daily by persons in charge of the wards. This data were compiled weekly and monthly figures were compiled using the mortality and morbidity surveillance form by the data manager of the hospital. Proofreading to ascertain correct figures was done for the data collected from all the respective units for quality control.

Ethical clearance

Ethical clearance for the study was obtained from the staff in charge of hospital since the hospital has no ethics review board. Study protocol followed the principles outlined in the Declaration of Helsinki.

Data management and analysis

Data obtained during the 5 years were summarized according to the presented conditions with respect to age groups and stratified by sex. The main outcome indicator was the number of patients that died in the hospital. Univariate analyses were carried out to examine the association between sex and mortality. In these analyses, chi-square tests were used. A two-tailed P-value of 0.1 or less was considered to be significant. Crude odds ratios (CORs) were obtained for years in which outcomes were significantly associated with sex.

Results

Major diagnoses across all age groups included uncomplicated malaria, acute watery diarrhea, anemia, presence of intestinal parasites, and urinary tract infection (Table 1). The main diagnoses among children age <5 years were malaria, acute watery diarrhea, and respiratory tract infections. Meningitis, tetanus, whooping cough, and conjunctivitis presented the least cases during the study period. There was an exponential increase in measles cases every other year and a decrease in the year that followed, by 2012. The reported number of patients with sexually transmitted diseases (STDs) almost doubled each year making a sixfold increase by 2012. These cases were, however, reported only among girls >5 years of age. The percentage of complicated cases among the cases of malaria that presented reduced from 30% to 20% by 2012. Trauma cases reported increased across the study period with a higher number of males than females across the study period.

Table 1

Disease patterns diagnosed and managed at Banadir Hospital between 2008 and 2012: number of cases managed, with respect to age groups and stratified by sex – with mortality associated with sex within each age group

Year Diagnosis/symptoms	2008					2009					2010					2011					2012
	<5 years		>5 years		Total	<5 years		>5 years		Total	<5 years		>5 years		Total	<5 years		>5 years		Total	<5 years		>5 years		Total
	M	F	M	F		M	F	M	F		M	F	M	F		M	F	M	F		M	F	M	F
Severe/complicated malaria	209	156	22	15	402	313	276	49	54	692	382	346	63	57	848	4,581	420	106	85	1,069	559	521	112	97	1,289
Uncomplicated malaria*	321	339	107	121	888	377	348	93	72	890	403	357	114	108	982	948	711	250	157	2,087	1,883	1,448	622	384	4,337
Bloody diarrhea	229	169	56	28	482	766	656	63	34	1,519	554	414	43	49	1,060	1,195	869	110	60	2,234	599	468	98	57	1,222
Acute watery diarrhea	2,408	2,239	482	584	5,744	2,191	2,002	407	453	5,053	1,644	1,376	320	311	3,651	3,996	3,202	1,651	1,512	1,031	3,276	2,770	888	1,058	7,992
Meningitis	83	66	10	8	167	97	78	14	12	201	104	82	13	8	207	187	174	26	24	415	295	232	69	40	636
Measles	9	5	1	1	16	84	82	7	8	181	37	35	5	3	80	1,016	802	140	89	2,074	644	540	171	96	1,451
Anemia	639	523	70	129	1,361	626	527	86	61	1,300	918	932	149	122	2,121	1,424	1,282	170	164	3,040	2,235	2,097	828	723	5,883
Skin infection	214	194	44	38	490	238	198	72	38	546	288	266	60	41	655	506	474	97	68	1,145	1,390	984	449	375	3,198
Respiratory infection/pneumonia	1,088	1,032	130	100	2,350	1,342	1,305	219	220	3,086	1,746	1,632	204	195	3,777	2,967	2,645	433	410	6,455	6,127	5,326	1,807	1,665	1,495
Intestinal parasites	600	582	110	108	1,400	619	540	127	122	1,408	943	977	126	113	2,159	1,550	1,439	198	201	3,388	2,996	2,734	1,102	1,086	7,918
Trauma	83	70	9	9	171	136	121	23	25	305	215	174	32	26	447	397	354	96	84	1,428	596	494	483	346	1,919
STD	0	0	0	576	576	0	0	0	449	449	0	0	0	872	872	0	0	0	1,122	1,122	0	0	0	2,933	2,933
Conjunctivitis	69	51	10	9	139	160	119	18	19	316	223	130	21	18	392	330	277	37	23	684	369	319	71	48	807
Suspected TB	68	51	29	21	169	323	202	193	130	848	107	101	69	33	310	119	84	73	62	328	230	232	153	141	756
Urinary tract infection	65	69	9	10	153	192	141	33	32	398	277	224	32	23	556	506	427	82	75	1,091	772	760	687	655	2,874
Tetanus	22	12	1	1	36	38	26	3	3	70	75	62	14	16	167	77	49	7	7	140	275	189	115	40	619
Whooping cough**	0	0	0	0	0	37	49	5	1	92	11	14	2	4	31	25	24	5	4	58	31	40	10	10	91
Others	359	340	60	53	812	443	319	142	123	1,027	637	540	381	289	1,847	1,258	936	304	292	2,568	1,356	1,326	1,550	1,483	5,715
Total cases	6,466	5,898	1,149	1,811	15,324	7,982	6,989	1,554	1,856	1,8381	8,565	7,667	1,651	2,288	20,171	16,504	14,194	3,801	4,864	39,354	23,633	20,480	9,215	11,237	64,588
Total deaths	189	133	15	12	349	158	119	20	13	310	147	123	117	14	401	179	150	29	21	379	302	245	76	61	684

Notes:

Cases confirmed by laboratory or RDT.

Cases of whooping cough were not recorded in 2008.

Abbreviations: F, female; M, male; RDT, rapid diagnostic test; STD, sexually transmitted disease; TB, tuberculosis.

Between 2008 and 2010, the number of cases at the diarrhea treatment center declined (Figure 1). There was an exponential increase from September 2010 to November 2011 and cases there after reduced gradually toward the end of 2012. Maximum numbers (1,485) were reported in August 2011. Monthly reporting of cases throughout the study period indicated that cases were higher between April and August each study year. Mortality due to diarrhea followed a similar pattern in both age groups (Table 2). Between 2008 and 2009, mortality declined in both age groups and increased between 2009 and 2011. There was a decline in mortality in 2012.

Figure 1

Number of diarrhea cases by month attended to at the diarrhea treatment center from January 2008 to December 2012.

Table 2

Diarrhea mortality rates per 1,000 among patients admitted to the pediatric unit, <5 and >5 years in males and females

Year	<5 years	>5 years
2008	24	25
2009	17	20
2010	22	29
2011	38	28
2012	14	16

Note: Mortality = (Total deaths/Total cases) × 1,000.

The number of live births at Banadir Hospital increased between 2008 and 2012; however, the number of stillbirths remained constant. The ratio of stillbirths to live births therefore declined over the study period (Figure 2). There was a consistent decline in the rate of stillbirths from 272 (per 1,000 live births) in 2008 to 102 in 2009. This reduced further to 71, 85, and 48 in 2010, 2011, and 2012, respectively. Death from neonatal tetanus stagnated at a mean rate of 27% for all the cases of neonatal tetanus presented.

Figure 2

Number and percentage of live births compared to stillbirths delivered at Banadir Hospital between 2008 and 2012.

The sum of total cases that were attended to at the hospital by the end of 2012 was four times the number at the baseline year of the study in 2008 (Figure 3), an increase from 15,324 to 64,588. The overall mortality rate among those admitted declined between 2008 and 2012 (Table 3). At a significant level of 0.1, however, mortality in the age group >5 years was consistently associated with sex across the study period (Table 4). The odds of dying for males compared to females in the age group >5 years were as follows: COR =1.98 (95% confidence interval [CI]: 0.9–4.3, P<0.1) in 2008; COR =1.85 (95% CI: 0.9–3.7, P<0.1) in 2009; COR =1.80 (95% CI: 0.8–3.7, P<0.1) in 2010; COR =1.77 (95% CI: 1.0–3.1, P<0.1) in 2011; and COR =1.52 (95% CI: 1.1–2.1, P<0.1) in 2012. Under-5 mortality was not consistently associated with the sex.

Figure 3

Number of patient admissions by month at Banadir Hospital from January 2009 to December 2012.

Table 3

Mortality rates per 1,000 among patients admitted to hospital, <5 and >5 years in males and females

Year	<5 years		>5 years
	Males	Females	Males	Females
2008	29	22	13	7
2009	20	17	13	7
2010	17	16	71	6
2011	10	11	8	4
2012	13	12	8	5

Note: Mortality = (Total deaths/Total cases) × 1,000.

Table 4

Mortality rates among children admitted to the hospital and COR for males in relation to females, by year

Sex and under-5 mortality
Year	Sex	Survived	Died	Chi-square value	P-value	COR (95% CI)
2008	Male	6,277	189	5.426	0.020*	1.31(1.0–1.6)
	Female	5,765	133			Ref
2009	Male	7,824	158	1.572	0.210
	Female	6,870	119
2010	Male	8,418	147	0.310	0.577
	Female	7,544	123
2011	Male	16,325	179	0.056	0.814
	Female	14,044	150
2012	Male	23,331	302	0.596	0.440
	Female	20,235	245
Sex and above-5 mortality
Year	Sex	Survived	Died	Chi-square value	P-value	COR (95% CI)
2008	Male	1,134	15	3.214	0.073*	1.99 (0.9–4.2)
	Female	1,799	12			Ref
2009	Male	1,534	20	3.037	0.081*	1.85 (0.9–3.7)
	Female	1,843	13			Ref
2010	Male	1,534	17	2.705	0.100	1.80 (0.8–3.7)
	Female	2,274	14			Ref
2011	Male	3,772	29	4.079	0.043*	1.77 (1.0–3.1)
	Female	4,843	21			Ref
2012	Male	9,139	76	6.047	0.014*	1.52 (1.1–2.1)
	Female	11,176	61			Ref

Notes: COR represents the odds of males dying in hospital compared to the females.

P-value significant level is <0.1.

Abbreviations: CI, confidence interval; COR, crude odds ratios; Ref, reference value.

Discussion

Disease patterns

Given the lack of data on a population level, this analysis aimed at understanding the patterns of conditions presented at Banadir Hospital in order to make inference and conclusions about the general health status of Banadir region. It is evident from the results that malaria, acute watery diarrhea, and respiratory tract infections dominated the continuum of causes of admissions despite the integrated community case management, a result that is consistent with World Health Organization findings.16 Although measles cases were on the rise, current data indicates that Banadir region is a high endemic area and findings could not be generalized to the entire population.17 Measles is one of the leading killers of young children particularly in the malnourished, a situation that is consistent with findings in Somalia. Measles immunization coverage remains low with less than one-third of children under 1 year vaccinated against measles.17

According to the African Union Mission in Somalia,18 cases of HIV are on the rise with low case detection due to the absence of diagnostics and stigma from the community.18 This could explain the annual doubling of STD cases although the rate of STDs was normal. Absence of STD cases among boys age >5 years, however, shows a gap in case detection since females are usually investigated at the maternity section. The reduction in the proportion of complicated cases of malaria indicates that there is improvement in early case detection and diagnosis for malaria within the catchment area for Banadir Hospital; however, data on case fatality were not available.

At the beginning of 2008, the gradual increase in the number of patients at Banadir Hospital was consistent with the country’s population increment.19 This trend; however, changed in mid-2010 (Figure 4) with an increase in the rate of hospitalization in relation to the population. This can be explained by the famine and hunger associated illnesses that the country faced during that time. Between 2010 and 2012, the United Nations reported the worst drought that ever hit Somalia in the last 60 years.20 The increased rate of hospitalization also implies that the hospital provides much more care now than before.

Figure 4

Comparison between changes in Somalia’s population in relation to the increase in the number of patients attended to in the hospital.

Notes: (A) Somalia’s population;19 (B) admissions at Banadir Hospital.

There was a clear relation between the annual rainfall pattern and that of diarrhea cases.21 In 2012, Médecins Sans Frontières documented the increased cases of acute watery diarrhea in southern Somalia,22 in line with findings of this study. The increase in cases observed between 2011 and 2012 could also be attributed to the cholera outbreak in the region. This was essentially due to poor sanitation, shortage of safe water, and overcrowding, which were exacerbated by the seasonal flooding of the Shebelle River.

A recent report by World Health Organization shows that trauma cases are on the rise,17 which has been highlighted in findings at the hospital. Violence and conflict continue to take a heavy toll on civilians in Somalia with escalating numbers of weapon-related injuries. Despite the conflict, the cause of trauma cases among children age <5 years needs to be investigated. The role of males in the civil strife has led to the increased numbers of trauma cases among males compared to the females.

There was no consistent association between sex and under-5 mortality in this study in contrast to previous studies.13,23 These studies found that male sex was not an independent predictor of mortality among hospitalized children <5 years of age in the presence of risk factors like age, associated comorbidities, and severity of respective illnesses.24 For the age group >5 years, sex was consistently associated with higher mortality among males. It was not possible to highlight possible risk factors because of the nature of the data. Although studies have shown that conflict overshadows the social and sex issues, rendering them “secondary” to the primary concern of safety and survival,25 further research in this area would yield better explanations. It is possible that males presented with more critical conditions than females; however, this could not be ascertained from the study data.

Health system implications

The overall reduction in hospital mortality despite the increased number of patients attended to over the years is indicative of the improvement in performance of the hospital. Although the World Bank reports an under-5 mortality rate of 146 in Somalia,26 this study was not able to highlight changes in mortality rate over time. It is important to reflect on the fact that the overall hospital under-5 mortality among admitted cases has reduced and to highlight the progress that has been made. The increase in the number of patients can also be attributed to the observed number of live births that was much higher than the death rate. The increase in live births at the hospital with no significant increase in stillbirths could explain the increase in the region’s population and also an increase in the number of patients attended to at the hospital during the study period. Somalia’s birth rate stands at 41 births per 1,000 population and the death rate reduced from 15.9 to 13.9 deaths per 1,000 population despite the fact that the country is at war.27 Owing to this, information from Banadir Hospital could be essential in evaluating health system performance and provide reliable facts on planning for this catchment area. According to the Performance Assessment Tool for Quality Improvement in Hospitals model, the increase in the number of patients attended to at the hospital with reduction in mortality is indicative of positive performance.28

Limitations

The study involved a large data set for making good comparisons and detecting trends over time, for the first time in 2 decades of war; however, the data were aggregated making it hard to perform detailed analyses and making more concrete conclusions. Categories had been prefixed before the data were collected, which could not allow flexibility in the data analysis. Analyzing trends in this context was not possible. Disease-specific mortality was not possible in the study, which would have provided a better analysis of conditions. There may have been a selection of more serious cases being admitted to the hospital, which may also distort the results; however, sufficient information on the primary health care system in this war setting was not readily available to back up some of our arguments.

Conclusion

Diseases of infectious origin dominated the continuum of cases attended to at the hospital, and hospital-based mortality reduced across the study period. Data from Banadir Hospital were consistent with findings from Banadir region although figures from hospital-based studies are higher than those in the general population. This data can be used to describe the health status of the community in the absence of credible demographic surveillance in Banadir region as earlier stated. Hospital-based studies would work as early surveillance tools in a sentinel site, since hospital cases may be observed to increase before the outbreak. Consistent use of hospital data could give credible public health reflections for Banadir region.

There was an association between mortality in the age group >5 years and sex with a protective advantage for females compared to males. Our results only reflect that there is a difference in outcome of patient admissions with respect to sex in the age group >5 years but do not show that the female sex is positioned better than the male. The situation of war and increased risk of injury for males should be put into context in this study. There are better outcomes at the hospital with progressive improvement during the study period; however, these outcomes are still low in comparison to global standards.