Literature DB >> 27618882

The Hypoxia Response Pathways - Hats Off!

M Celeste Simon1.   

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Year:  2016        PMID： 27618882      PMCID： PMC5541993          DOI： 10.1056/NEJMcibr1610065

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   91.245


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  6 in total

1.  The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.

Authors:  P H Maxwell; M S Wiesener; G W Chang; S C Clifford; E C Vaux; M E Cockman; C C Wykoff; C W Pugh; E R Maher; P J Ratcliffe
Journal:  Nature       Date:  1999-05-20       Impact factor: 49.962

2.  C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

Authors:  A C Epstein; J M Gleadle; L A McNeill; K S Hewitson; J O'Rourke; D R Mole; M Mukherji; E Metzen; M I Wilson; A Dhanda; Y M Tian; N Masson; D L Hamilton; P Jaakkola; R Barstead; J Hodgkin; P H Maxwell; C W Pugh; C J Schofield; P J Ratcliffe
Journal:  Cell       Date:  2001-10-05       Impact factor: 41.582

3.  Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.

Authors:  P Jaakkola; D R Mole; Y M Tian; M I Wilson; J Gielbert; S J Gaskell; A von Kriegsheim; H F Hebestreit; M Mukherji; C J Schofield; P H Maxwell; C W Pugh; P J Ratcliffe
Journal:  Science       Date:  2001-04-05       Impact factor: 47.728

4.  HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.

Authors:  M Ivan; K Kondo; H Yang; W Kim; J Valiando; M Ohh; A Salic; J M Asara; W S Lane; W G Kaelin
Journal:  Science       Date:  2001-04-05       Impact factor: 47.728

5.  Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein.

Authors:  O Iliopoulos; A P Levy; C Jiang; W G Kaelin; M A Goldberg
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

6.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

Authors:  G L Wang; B H Jiang; E A Rue; G L Semenza
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205
  6 in total
  16 in total

Review 1.  Eight Kinetically Stable but Thermodynamically Activated Molecules that Power Cell Metabolism.

Authors:  Christopher T Walsh; Benjamin P Tu; Yi Tang
Journal:  Chem Rev       Date:  2017-12-22       Impact factor: 60.622

2.  HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma.

Authors:  Kevin D Courtney; Yuanqing Ma; Alberto Diaz de Leon; Alana Christie; Zhiqun Xie; Layton Woolford; Nirmish Singla; Allison Joyce; Haley Hill; Ananth J Madhuranthakam; Qing Yuan; Yin Xi; Yue Zhang; Jenny Chang; Oluwatomilade Fatunde; Yull Arriaga; Arthur E Frankel; Sanjeeva Kalva; Song Zhang; Tiffani McKenzie; Oscar Reig Torras; Robert A Figlin; Brian I Rini; Renée M McKay; Payal Kapur; Tao Wang; Ivan Pedrosa; James Brugarolas
Journal:  Clin Cancer Res       Date:  2019-11-14       Impact factor: 12.531

3.  Rabeprazole Promotes Vascular Repair and Resolution of Sepsis-Induced Inflammatory Lung Injury through HIF-1α.

Authors:  Colin E Evans; Yi Peng; Maggie M Zhu; Zhiyu Dai; Xianming Zhang; You-Yang Zhao
Journal:  Cells       Date:  2022-04-22       Impact factor: 7.666

4.  Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells.

Authors:  Kai Wang; Xiaozhen Dai; Junhong He; Xiaoqing Yan; Chengkui Yang; Xia Fan; Shiyue Sun; Jing Chen; Jianxiang Xu; Zhongbin Deng; Jiawei Fan; Xiaohuan Yuan; Hairong Liu; Edward C Carlson; Feixia Shen; Kupper A Wintergerst; Daniel J Conklin; Paul N Epstein; Chaosheng Lu; Yi Tan
Journal:  Diabetes       Date:  2020-05-13       Impact factor: 9.461

5.  The Pathophysiological Sequence of Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Male Mice.

Authors:  Robert S Weinstein; Erin A Hogan; Michael J Borrelli; Serguei Liachenko; Charles A O'Brien; Stavros C Manolagas
Journal:  Endocrinology       Date:  2017-11-01       Impact factor: 4.736

Review 6.  Putative roles of SLC7A5 (LAT1) transporter in pain.

Authors:  Sascha R A Alles; Kimberly Gomez; Aubin Moutal; Rajesh Khanna
Journal:  Neurobiol Pain       Date:  2020-06-30

7.  Impairment of hypoxia-induced angiogenesis by LDL involves a HIF-centered signaling network linking inflammatory TNFα and angiogenic VEGF.

Authors:  Fengyan Jin; Xiangyu Zheng; Yanping Yang; Gang Yao; Long Ye; Thorsten R Doeppner; Dirk M Hermann; Haifeng Wang; Yun Dai
Journal:  Aging (Albany NY)       Date:  2019-01-18       Impact factor: 5.682

8.  Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation.

Authors:  Miguel Alejandro Lopez-Ramirez; Catherine Chinhchu Lai; Shady Ibrahim Soliman; Preston Hale; Angela Pham; Esau J Estrada; Sara McCurdy; Romuald Girard; Riya Verma; Thomas Moore; Rhonda Lightle; Nicholas Hobson; Robert Shenkar; Orit Poulsen; Gabriel G Haddad; Richard Daneman; Brendan Gongol; Hao Sun; Frederic Lagarrigue; Issam A Awad; Mark H Ginsberg
Journal:  J Clin Invest       Date:  2021-07-01       Impact factor: 19.456

9.  Suppression of mitochondrial oxygen metabolism mediated by the transcription factor HIF-1 alleviates propofol-induced cell toxicity.

Authors:  Chisato Sumi; Akihisa Okamoto; Hiromasa Tanaka; Munenori Kusunoki; Tomohiro Shoji; Takeo Uba; Takehiko Adachi; Teppei Iwai; Kenichiro Nishi; Hiroshi Harada; Hidemasa Bono; Yoshiyuki Matsuo; Kiichi Hirota
Journal:  Sci Rep       Date:  2018-06-12       Impact factor: 4.379

Review 10.  Neurovascular patterning cues and implications for central and peripheral neurological disease.

Authors:  Nicholas T Gamboa; Philipp Taussky; Min S Park; William T Couldwell; Mark A Mahan; M Yashar S Kalani
Journal:  Surg Neurol Int       Date:  2017-09-06
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