Literature DB >> 2761384

In vivo localized ESR spectroscopy reflecting metabolism.

G Bacic1, M J Nilges, R L Magin, T Walczak, H M Swartz.   

Abstract

Localized electron spin resonance spectroscopy in live mice was performed using a surface coil operating at 1.1 GHz with sufficient sensitivity and stability to measure quantitatively the time course of the distribution, uptake, and reduction of nitroxides in selected organs/regions (liver, bladder, head) of mice. The ability to measure regional concentrations of nitroxides in vivo could be used for pharmacokinetic analysis of drugs labeled with nitroxides and for measurement of oxygen concentrations and redox metabolism.

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Year:  1989        PMID： 2761384     DOI： 10.1002/mrm.1910100211

Source DB:  PubMed          Journal:  Magn Reson Med        ISSN： 0740-3194            Impact factor:   4.668


  16 in total

1.  An analysis of the intracerebral ability to eliminate a nitroxide radical in the rat after administration of idebenone by an in vivo rapid scan electron spin resonance spectrometer.

Authors:  H Yokoyama; N Tsuchihashi; T Ogata; M Hiramatsu; N Mori
Journal:  MAGMA       Date:  1996 Sep-Dec       Impact factor: 2.310

2.  In vivo evaluation of the effect of zonisamide on the hippocampal redox state during kainic acid-induced seizure status in rats.

Authors:  Yuto Ueda; Taku Doi; Jun Tokumaru; Akira Nakajima; Keiko Nagatomo
Journal:  Neurochem Res       Date:  2005-09       Impact factor: 3.996

3.  Young Investigator Award presentation at the 13th Annual Meeting of the ESMRMB, September 1996, Prague. A proton-electron double-resonance imaging apparatus with simultaneous multiple electron paramagnetic resonance irradiation at 10 mT.

Authors:  M Alecci; D J Lurie; I Nicholson; G Placidi; A Sotgiu
Journal:  MAGMA       Date:  1996 Sep-Dec       Impact factor: 2.310

4.  Heterogeneity of regional redox status and relation of the redox status to oxygenation in a tumor model, evaluated using electron paramagnetic resonance imaging.

Authors:  Keizo Takeshita; Kumiko Kawaguchi; Kaori Fujii-Aikawa; Megumi Ueno; Shoko Okazaki; Mitsuhiro Ono; Murali C Krishna; Periannan Kuppusamy; Toshihiko Ozawa; Nobuo Ikota
Journal:  Cancer Res       Date:  2010-05-04       Impact factor: 12.701

Review 5.  Theory, instrumentation, and applications of electron paramagnetic resonance oximetry.

Authors:  Rizwan Ahmad; Periannan Kuppusamy
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

Review 6.  Exchange Phenomena in the Electron Paramagnetic Resonance Spectra of the Nitroxyl and Trityl Radicals: Multifunctional Spectroscopy and Imaging of Local Chemical Microenvironment.

Authors:  Valery V Khramtsov; Andrey A Bobko; Mark Tseytlin; Benoit Driesschaert
Journal:  Anal Chem       Date:  2017-04-10       Impact factor: 6.986

7.  In vivo evaluation of hippocampal anti-oxidant ability of zonisamide in rats.

Authors:  J Tokumaru; Y Ueda; H Yokoyama; A Nakajima; T Doi; Y Mitsuyama; H Ohya-Nishiguchi; H Kamada
Journal:  Neurochem Res       Date:  2000-08       Impact factor: 3.996

Review 8.  In Vivo Molecular Electron Paramagnetic Resonance-Based Spectroscopy and Imaging of Tumor Microenvironment and Redox Using Functional Paramagnetic Probes.

Authors:  Valery V Khramtsov
Journal:  Antioxid Redox Signal       Date:  2017-12-20       Impact factor: 8.401

9.  Reducing ability of the striatum and cerebral cortex in rats following acute administration of risperidone or haloperidol: an estimation by in vivo electron paramagnetic resonance imaging.

Authors:  Hidekatsu Yokoyama; Osamu Itoh; Hiroaki Ohya-Nishiguchi; Hitoshi Kamada
Journal:  Neurochem Res       Date:  2002-03       Impact factor: 3.996

10.  Simultaneous 280 MHz EPR imaging of rat organs during nitroxide free radical clearance.

Authors:  M Alecci; M Ferrari; V Quaresima; A Sotgiu; C L Ursini
Journal:  Biophys J       Date:  1994-09       Impact factor: 4.033
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