Yoon-Ho Kim1, Sung-In Kim2, Seongjun Park3, Sung Hwan Hong4, Sun G Chung5. 1. Harvard-MIT Health Sciences and Technology, and Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA(∗). 2. College of Medicine, Seoul National University, Seoul, South Korea(†). 3. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA(‡). 4. Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, South Korea(§). 5. Department of Rehabilitation Medicine, Seoul National University College of Medicine & Hospital, 101 Daehak-ro, Jongno-gu, Seoul 110-744, South Korea; Rheumatism Research Institute, Medical Research Center, Seoul National University, Seoul, South Korea; and Institute of Aging, Seoul National University, Seoul, South Korea(¶). Electronic address: suncg@snu.ac.kr.
Abstract
BACKGROUND: We theorized that active cervical extension should influence the position of the nucleus pulposus (NP) within the intervertebral disk (IVD) in the sagittal plane. Although several studies on the lumbar IVD have been conducted, there are no quantitative data for in vivo positional changes of the NP in the cervical IVD. OBJECTIVE: To evaluate the influence and mechanism of cervical extension on the deformation and migration of IVD and NP in the sagittal plane and understand underlying mechanisms of the extension maneuver. DESIGN: Asymptomatic subjects underwent magnetic resonance imaging while supine with their cervical spines in neutral and extended positions. SETTING: Academic medical center. PARTICIPANTS: Ten young, healthy male participants (age range 19-30 years; mean 22.4 ± 1.64 years). METHODS: T2-weighted sagittal images from C3-C4 to C6-C7 of subjects in both neutral and extension positions were analyzed. MAIN OUTCOME MEASUREMENTS: Deformation of IVD and positional change of NP were quantified and compared between neutral and extension positions. Intersegmental angles between vertebrae, horizontal positions of anterior and posterior IVD and NP margins, IVD outer and inner heights, and sagittal morphology of NP were quantified and compared between the neutral and extension positions. Correlations between the measured parameters and segmental extension angle were also investigated. RESULTS: Anterior and posterior IVD margins moved posteriorly with respect to the vertebral body in extension. Both NP margins remained unchanged relative to the vertebral body but moved anteriorly with respect to the IVD. IVD outer and inner heights in the anterior region increased in extension, and morphological changes of the NP were less noticeable when compared with its relative migration within the IVD. Most of the intradiskal changes were linearly correlated with the segmental extension angle. CONCLUSIONS: Cervical extension induces anterior migration of the NP away from the posterior disk margin and may have a clinical effect on diskogenic neck pain resulting from internal disk disruption. LEVEL OF EVIDENCE: Not applicable.
BACKGROUND: We theorized that active cervical extension should influence the position of the nucleus pulposus (NP) within the intervertebral disk (IVD) in the sagittal plane. Although several studies on the lumbar IVD have been conducted, there are no quantitative data for in vivo positional changes of the NP in the cervical IVD. OBJECTIVE: To evaluate the influence and mechanism of cervical extension on the deformation and migration of IVD and NP in the sagittal plane and understand underlying mechanisms of the extension maneuver. DESIGN: Asymptomatic subjects underwent magnetic resonance imaging while supine with their cervical spines in neutral and extended positions. SETTING: Academic medical center. PARTICIPANTS: Ten young, healthy male participants (age range 19-30 years; mean 22.4 ± 1.64 years). METHODS: T2-weighted sagittal images from C3-C4 to C6-C7 of subjects in both neutral and extension positions were analyzed. MAIN OUTCOME MEASUREMENTS: Deformation of IVD and positional change of NP were quantified and compared between neutral and extension positions. Intersegmental angles between vertebrae, horizontal positions of anterior and posterior IVD and NP margins, IVD outer and inner heights, and sagittal morphology of NP were quantified and compared between the neutral and extension positions. Correlations between the measured parameters and segmental extension angle were also investigated. RESULTS: Anterior and posterior IVD margins moved posteriorly with respect to the vertebral body in extension. Both NP margins remained unchanged relative to the vertebral body but moved anteriorly with respect to the IVD. IVD outer and inner heights in the anterior region increased in extension, and morphological changes of the NP were less noticeable when compared with its relative migration within the IVD. Most of the intradiskal changes were linearly correlated with the segmental extension angle. CONCLUSIONS: Cervical extension induces anterior migration of the NP away from the posterior disk margin and may have a clinical effect on diskogenic neck pain resulting from internal disk disruption. LEVEL OF EVIDENCE: Not applicable.
Authors: Robert L Wilson; Leah Bowen; Woong Kim; Luyao Cai; Stephanie Ellyse Schneider; Eric A Nauman; Corey P Neu Journal: Sci Rep Date: 2021-01-12 Impact factor: 4.379