Literature DB >> 27613382

Nutraceuticals: A paradigm of proactive medicine.

Antonello Santini1, Gian Carlo Tenore2, Ettore Novellino2.   

Abstract

Nutraceuticals define a new category which shades the frontier between drugs and food. As per its definition, a nutraceutical is "a food or part of a food that provides benefits health in addition to its nutritional content". Active substances either way extracted from plants (phytocomplexes) or of animal origin, when extracted, concentrated and administered in a suitable pharmaceutical form, can create a very promising toolbox useful to prevent and/or support the therapy of some pathologic conditions given their proven clinical efficacy. It is worldwide recognized that diet and lifestyle are essential to promote and maintain well-being and nice-being condition, other than help to prevent diseases possible onset. Both non-correct dietary habits and lifestyle can in fact determine pathological conditions. The metabolic syndrome, a worldwide epidemic threat, can be named an outstanding example. This syndrome is characterized by a cascade of cardio metabolic risk factors which include obesity, insulin resistance, hypertension, and dyslipidemia. Prevention is the key strategy for an effective proactive medicine, in which efforts are addressed to prevention and, consequently, to lower the risk connected to some lifestyle related diseases reducing, at the same time, any National Health Systems cost needed to guarantee the proper therapeutic approach based on pharmaceuticals. Nutraceuticals use in prevention is a proactive reverse approach tool to pre-clinical health conditions. They can be effectively used, by including in the daily diet, in an area which shades in the range "beyond the diet, before drugs", since they combine both nutritional and beneficial healthy properties of food extracts with the healing properties of natural active compounds.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Food; Health; Nutraceuticals; Prevention; Proactive medicine; Therapy; Watchful medicine

Mesh:

Year:  2016        PMID: 27613382     DOI: 10.1016/j.ejps.2016.09.003

Source DB:  PubMed          Journal:  Eur J Pharm Sci        ISSN: 0928-0987            Impact factor:   4.384


  54 in total

Review 1.  Nutraceuticals as modulators of gut microbiota: Role in therapy.

Authors:  Eamonn M M Quigley
Journal:  Br J Pharmacol       Date:  2020-01-03       Impact factor: 8.739

Review 2.  Nutraceuticals: Reviewing their Role in Chronic Disease Prevention and Management.

Authors:  Amanda Bergamin; Evangeline Mantzioris; Giordana Cross; Permal Deo; Sanjay Garg; Alison M Hill
Journal:  Pharmaceut Med       Date:  2019-08

3.  Novel soybean-based high protein bar rich in isoflavones improves insulin sensitivity in diabetic Wistar rats.

Authors:  Wanessa Costa Silva Faria; Morenna Alana Giordani; Ariadny da Silva Arcas; Daniela Fernanda Lima Carvalho Cavenaghi; Adriana Paiva de Oliveira; Jacqueline Fiuza Dos Santos; Wander Miguel Barros
Journal:  J Food Sci Technol       Date:  2017-11-04       Impact factor: 2.701

4.  To Nutraceuticals and Back: Rethinking a Concept.

Authors:  Antonello Santini; Ettore Novellino
Journal:  Foods       Date:  2017-09-05

Review 5.  Nutraceuticals: opening the debate for a regulatory framework.

Authors:  Antonello Santini; Silvia Miriam Cammarata; Giacomo Capone; Angela Ianaro; Gian Carlo Tenore; Luca Pani; Ettore Novellino
Journal:  Br J Clin Pharmacol       Date:  2018-02-14       Impact factor: 4.335

6.  Polyphenolic Compounds of Crataegus Berry, Leaf, and Flower Extracts Affect Viability and Invasive Potential of Human Glioblastoma Cells.

Authors:  Natalia Żurek; Olena Karatsai; Maria Jolanta Rędowicz; Ireneusz Tomasz Kapusta
Journal:  Molecules       Date:  2021-05-01       Impact factor: 4.411

7.  Characteristics of Newly Developed Extruded Products Supplemented with Plants in a Form of Microwave-Expanded Snacks.

Authors:  Katarzyna Lisiecka; Agnieszka Wójtowicz; Marek Gancarz
Journal:  Materials (Basel)       Date:  2021-05-24       Impact factor: 3.623

8.  Development and Optimization of Supercritical Fluid Extraction Setup Leading to Quantification of 11 Cannabinoids Derived from Medicinal Cannabis.

Authors:  Sadia Qamar; Yady J Manrique; Harendra S Parekh; James R Falconer
Journal:  Biology (Basel)       Date:  2021-05-28

9.  Amaranthus caudatus Stimulates Insulin Secretion in Goto-Kakizaki Rats, a Model of Diabetes Mellitus Type 2.

Authors:  Silvia Zambrana; Lena C E Lundqvist; Virginia Veliz; Sergiu-Bogdan Catrina; Eduardo Gonzales; Claes-Göran Östenson
Journal:  Nutrients       Date:  2018-01-15       Impact factor: 5.717

10.  Liver and intestinal protective effects of Castanea sativa Mill. bark extract in high-fat diet rats.

Authors:  Roberta Budriesi; Fabio Vivarelli; Donatella Canistro; Rita Aldini; Clara Babot Marquillas; Ivan Corazza; Romana Fato; Silvia Cirillo; Christian Bergamini; Antonia D'Errico; Cristiano Bolchi; Monica Cevenini; Alessio Degiovanni; Maria Frosini; Luca Camarda; Alberto Chiarini; Matteo Micucci
Journal:  PLoS One       Date:  2018-08-06       Impact factor: 3.240

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