Hideo Takahashi1, Nisar Zaidi2, Eren Berber3,4. 1. Department of General Surgery, Cleveland Clinic, Ohio. 2. Department of Endocrine Surgery, Cleveland Clinic, Ohio. 3. Department of General Surgery, Cleveland Clinic, Ohio. berbere@ccf.org. 4. Department of Endocrine Surgery, Cleveland Clinic, Ohio. berbere@ccf.org.
Abstract
BACKGROUND: There has been a recent interest in the use of Indocyanine green (ICG) imaging. The aim of this study is to review our initial experience in liver surgery. METHODS: ICG fluorescent imaging was used in 15 patients undergoing surgical treatment of their liver tumors between 2015 and 2016. ICG imaging was initially performed, followed by intraoperative ultrasound (IOUS). Findings on fluorescence were compared with preoperative cross-sectional imaging and IOUS. RESULT: Sixty-two lesions were identified, with 34 located superficially and 28 deeply in the liver. While 13 patients underwent surgery for malignant liver metastases, two patients had operations for benign liver diseases. Seven patients underwent open or robotic liver resections, five laparoscopic microwave liver ablation, and three diagnostic laparoscopy. ICG identified all of the superficial lesions. IOUS identified 98% of all lesions. The most benefit of ICG was in showing the margins of the superficial lesions in real-time and guiding surgical treatment, which was limited by IOUS. CONCLUSION: This is the first North American study to evaluate the potential utility of ICG during liver surgery. Its major benefit seems to be in providing real-time feedback to the surgeon about the margins of superficial tumors for resection or ablation. J. Surg. Oncol. 2016;114:625-629.
BACKGROUND: There has been a recent interest in the use of Indocyanine green (ICG) imaging. The aim of this study is to review our initial experience in liver surgery. METHODS:ICG fluorescent imaging was used in 15 patients undergoing surgical treatment of their liver tumors between 2015 and 2016. ICG imaging was initially performed, followed by intraoperative ultrasound (IOUS). Findings on fluorescence were compared with preoperative cross-sectional imaging and IOUS. RESULT: Sixty-two lesions were identified, with 34 located superficially and 28 deeply in the liver. While 13 patients underwent surgery for malignant liver metastases, two patients had operations for benign liver diseases. Seven patients underwent open or robotic liver resections, five laparoscopic microwave liver ablation, and three diagnostic laparoscopy. ICG identified all of the superficial lesions. IOUS identified 98% of all lesions. The most benefit of ICG was in showing the margins of the superficial lesions in real-time and guiding surgical treatment, which was limited by IOUS. CONCLUSION: This is the first North American study to evaluate the potential utility of ICG during liver surgery. Its major benefit seems to be in providing real-time feedback to the surgeon about the margins of superficial tumors for resection or ablation. J. Surg. Oncol. 2016;114:625-629.
Authors: Medical Association Of Chinese Medical Association Digital; Intelligent Surgery Professional Committee Of Chinese Research Hospital Digital; Cancer Professional Committee Of Chinese Medical Doctor Association Liver; Precise Medicine Professional Committee Clinical; Imaging And Equipment Professional Committee Of China Graphics Society Medical; Imaging Professional Committee Of China Biophysical Society Molecular Journal: Nan Fang Yi Ke Da Xue Xue Bao Date: 2019-10-30
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