Literature DB >> 27610751

Targeting transcriptional co-activators in advanced prostate cancer.

Anna C Groner1,2, Myles Brown1,2, Jean-Philippe Theurillat3,4.   

Abstract

Entities:  

Keywords:  Bromodomain; LXXLL motif; TRIM24; prostate cancer progression; targeting androgen receptor-mediated transcription

Mesh：

Substances：

Year:  2016        PMID： 27610751      PMCID： PMC5224444          DOI： 10.1080/15384101.2016.1229019

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


× No keyword cloud information.
  7 in total

1.  Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1.

Authors:  Ying Wang; David M Lonard; Yang Yu; Dar-Chone Chow; Timothy G Palzkill; Jin Wang; Ruogu Qi; Alexander J Matzuk; Xianzhou Song; Franck Madoux; Peter Hodder; Peter Chase; Patrick R Griffin; Suoling Zhou; Lan Liao; Jianming Xu; Bert W O'Malley
Journal:  Cancer Res       Date:  2014-01-03       Impact factor: 12.701

2.  Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.

Authors:  Wylie S Palmer; Guillaume Poncet-Montange; Gang Liu; Alessia Petrocchi; Naphtali Reyna; Govindan Subramanian; Jay Theroff; Anne Yau; Maria Kost-Alimova; Jennifer P Bardenhagen; Elisabetta Leo; Hannah E Shepard; Trang N Tieu; Xi Shi; Yanai Zhan; Shuping Zhao; Michelle C Barton; Giulio Draetta; Carlo Toniatti; Philip Jones; Mary Geck Do; Jannik N Andersen
Journal:  J Med Chem       Date:  2015-07-06       Impact factor: 7.446

Review 3.  Nuclear receptor coactivators: master regulators of human health and disease.

Authors:  Subhamoy Dasgupta; David M Lonard; Bert W O'Malley
Journal:  Annu Rev Med       Date:  2013-09-16       Impact factor: 13.739

4.  TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer.

Authors:  Anna C Groner; Laura Cato; Jonas de Tribolet-Hardy; Tiziano Bernasocchi; Hana Janouskova; Diana Melchers; René Houtman; Andrew C B Cato; Patrick Tschopp; Lei Gu; Andrea Corsinotti; Qing Zhong; Christian Fankhauser; Christine Fritz; Cédric Poyet; Ulrich Wagner; Tiannan Guo; Ruedi Aebersold; Levi A Garraway; Peter J Wild; Jean-Philippe Theurillat; Myles Brown
Journal:  Cancer Cell       Date:  2016-05-26       Impact factor: 31.743

5.  Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.

Authors:  Irfan A Asangani; Vijaya L Dommeti; Xiaoju Wang; Rohit Malik; Marcin Cieslik; Rendong Yang; June Escara-Wilke; Kari Wilder-Romans; Sudheer Dhanireddy; Carl Engelke; Mathew K Iyer; Xiaojun Jing; Yi-Mi Wu; Xuhong Cao; Zhaohui S Qin; Shaomeng Wang; Felix Y Feng; Arul M Chinnaiyan
Journal:  Nature       Date:  2014-04-23       Impact factor: 49.962

Review 6.  Targeting the androgen receptor pathway in prostate cancer.

Authors:  Yu Chen; Charles L Sawyers; Howard I Scher
Journal:  Curr Opin Pharmacol       Date:  2008-08-12       Impact factor: 5.547

7.  Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.

Authors:  James Bennett; Oleg Fedorov; Cynthia Tallant; Octovia Monteiro; Julia Meier; Vicky Gamble; Pavel Savitsky; Graciela A Nunez-Alonso; Bernard Haendler; Catherine Rogers; Paul E Brennan; Susanne Müller; Stefan Knapp
Journal:  J Med Chem       Date:  2015-05-20       Impact factor: 7.446
  7 in total
  1 in total

Review 1.  Role of steroid receptor and coregulator mutations in hormone-dependent cancers.

Authors:  Anna C Groner; Myles Brown
Journal:  J Clin Invest       Date:  2017-04-03       Impact factor: 14.808
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.