Literature DB >> 27610063

Prevalence and risk factors of gastroparesis-related symptoms among patients with type 2 diabetes.

Rakan A Almogbel1, Fulwa A Alhussan2, Sulaiman A Alnasser3, Metab A Algeffari4.   

Abstract

BACKGROUND: The prevalence of gastroparesis in type 2 diabetes mellitus (T2DM) vary widely. Our aim is to estimate the prevalence of clinical symptoms of gastroparesis among patients with type 2 diabetes mellitus and explore the relationship between gastroparesis and other risk factors.
METHODS: A cross-sectional study evaluating 147 type 2 diabetics using the Gastroparesis Cardinal Symptoms Index (GCSI). A GCSI Total Score ≥ 1.90 were chosen as having definite symptoms of gastroparesis. All patients completed a demographic questionnaire and interviewed to complete the. Demographic Data, disease duration, Medication, comorbidities, recent blood glucose and HbA1C were collected and investigated.
RESULTS: The prevalence of clinical symptoms of gastroparesis among type 2 diabetics was 10.8%. Clinical symptoms of gastroparesis were significantly correlated to HbA1c (p=0.001), blood glucose (p= 0.003), duration of diabetes (p= 0.02) and comorbidities (p=0.009). The most common symptoms were bloating, stomach fullness and early satiety (63.94%, 55.1% and 48.3% respectively). In logistic regression analysis, female gender emerged as significant independent predictors of the presence of at least one symptom.
CONCLUSIONS: The prevalence of clinical symptoms of gastroparesis observed in the Saudi patientsdiagnosedwithtype2 diabetes was 10.8% and is independently associated with poor controlled diabetes, hyperglycemia, and long duration of diabetes and history of Co-morbid conditions.

Entities:  

Year:  2016        PMID: 27610063      PMCID: PMC5003583     

Source DB:  PubMed          Journal:  Int J Health Sci (Qassim)        ISSN: 1658-3639


  28 in total

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7.  Development and validation of a patient-assessed gastroparesis symptom severity measure: the Gastroparesis Cardinal Symptom Index.

Authors:  D A Revicki; A M Rentz; D Dubois; P Kahrilas; V Stanghellini; N J Talley; J Tack
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8.  Current practice in the management of patients with type 2 diabetes mellitus in Saudi Arabia.

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9.  Gender-related differences in gastric emptying.

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3.  Prevalence of cardiovascular autonomic neuropathy and gastroparesis symptoms among patients with type 2 diabetes who attend a primary health care center.

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5.  Pharmacological Approaches to Diabetic Gastroparesis: A systematic review of randomised clinical trials.

Authors:  Mohammad Z Asha; Sundos F H Khalil
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