Literature DB >> 2760944

Intracerebroventricular administration of bombesin inhibits biliary and gastric secretion in the rat.

C Z Yao1, D G MacLellan, J C Thompson.   

Abstract

The effect of intracerebroventricular (ICV) bombesin on bile and gastric acid secretion was examined in the rat. ICV bombesin (10 micrograms in 10 microliters) inhibited basal biliary volume by 27% and bile bicarbonate by 52% of control values, while gastric acid secretion was decreased by 75%. These results provide evidence for central mechanisms for the control of gastrointestinal function.

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Year:  1989        PMID: 2760944     DOI: 10.1002/jnr.490220412

Source DB:  PubMed          Journal:  J Neurosci Res        ISSN: 0360-4012            Impact factor:   4.164


  2 in total

1.  Regulation of hepatic function by brain neuropeptides.

Authors:  Masashi Yoneda
Journal:  World J Gastroenterol       Date:  1998-06       Impact factor: 5.742

2.  Intracerebroventricular neuropeptide Y stimulates bile secretion via a vagal mechanism.

Authors:  M Farouk; J G Geoghegan; R S Pruthi; H J Thomson; T N Pappas; W C Meyers
Journal:  Gut       Date:  1992-11       Impact factor: 23.059

  2 in total

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