| Literature DB >> 27609233 |
V D Nikitushkin1, M O Shleeva2, A I Zinin3, K A Trutneva2, D N Ostrovsky2, A S Kaprelyants2.
Abstract
Upon transition of Mycobacterium smegmatis into the dormant state, accumulation of a dark brown fluorescent pigment was observed. This pigment gave bright red fluorescence in both cells and the culture medium. Based on 1H-NMR, MALDI and UV spectra, the fluorescent compounds, extracted from the culture medium as well as from the dormant cells, were concluded to be a mixture of free coproporphyrin III and uroporphyrin III and their corresponding methyl esters. A possible significance of porphyrin pigment accumulation in the dormant cells is discussed. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.Entities:
Keywords: MALDI; Mycobacteria; Mycobacterium smegmatis; dormancy; pigmentation; porphyrins
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Year: 2016 PMID： 27609233 DOI： 10.1093/femsle/fnw206
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742