Literature DB >> 27608891

Preliminary study on diagnosis of lumbar disc degeneration with magnetic resonance T1p, T2 mapping and DWI quantitative detection technologies.

Y-Z Cui1, X-H Yang, P-F Liu, B Wang, W-J Chen.   

Abstract

OBJECTIVE: The value of diagnosing lumbar disc degeneration with T1p magnetic resonance imaging (MRI), T2 mapping and diffusion-weighted imaging (DWI) technologies. PATIENTS AND METHODS: We selected 30 patients diagnosed with lumbar disc herniation (group A), 30 patients with lumbar disc degeneration (group B) and 30 healthy volunteers (group C) and carried out Pfirrmann grading of intervertebral discs (L1-S1 segment) based on conventional T2WI median sagittal images. T1p, T2 mapping and DWI were then applied.
RESULTS: Group A primarily had Pfirrmann grades of III-IV, group B had Pfirrmann grades of I-IV and group C had Pfirmann grades of I-II. The differences between the groups were statistically significant (p <0.05). The average T1p, T2 mapping and apparent diffusion coefficient (ADC) values of the nucleus pulposus and annulus fibrosus in group A were significantly lower than in group B. The highest values were in group C, and the differences were statistically significant (p <0.05).
CONCLUSIONS: T2WI, T1p MRI, T2 Mapping and DWI technologies have different capacities to diagnose lumbar disc degeneration, and have great value in improving diagnostic accuracy.

Entities:  

Mesh:

Year:  2016        PMID: 27608891

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  7 in total

1.  Ultrashort time-to-echo T2* and T2* relaxometry for evaluation of lumbar disc degeneration: a comparative study.

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2.  Research on the function and related mechanism of P27 gene in the intervertebral disc degeneration of mice.

Authors:  Xiao Liu; Deguo Wang; Zhengzheng Zhang; Fenghui Zhu; Aiming Yao; Jiwei Tian; Dengshun Miao
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3.  Feasibility of T2 Mapping and Magnetic Transfer Ratio for Diagnosis of Intervertebral Disc Degeneration at the Cervicothoracic Junction: A Pilot Study.

Authors:  Chao Zhang; Yuan Lin; Zhihua Han; Liang Gao; Ruipeng Guo; Qinglei Shi; Lei Chen; Chun Chen
Journal:  Biomed Res Int       Date:  2019-05-02       Impact factor: 3.411

Review 4.  Imaging in Spine Surgery: Current Concepts and Future Directions.

Authors:  Garrett K Harada; Zakariah K Siyaji; Sadaf Younis; Philip K Louie; Dino Samartzis; Howard S An
Journal:  Spine Surg Relat Res       Date:  2019-11-01

5.  Exploratory clinical trial on the safety and capability of dMD-001 in lumbar disc herniation: Study protocol for a first-in-human pilot study.

Authors:  Katsuhisa Yamada; Maeda Kenichiro; Yoichi M Ito; Fujio Inage; Toshiyuki Isoe; Nozomi Yokota; Osamu Sugita; Norihiro Sato; Khin Khin Tha; Norimasa Iwasaki; Teruyo Arato; Hideki Sudo
Journal:  Contemp Clin Trials Commun       Date:  2021-06-29

6.  Quantitative evaluation of lumbar intervertebral disc degeneration by axial T2* mapping.

Authors:  Leitao Huang; Yuan Liu; Yi Ding; Xia Wu; Ning Zhang; Qi Lai; Xianjun Zeng; Zongmiao Wan; Min Dai; Bin Zhang
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

7.  Curative effect of posterior lumbar interbody fusion in the treatment of single-segment lumbar degenerative disease and changes in adjacent segment quantitative score.

Authors:  Yan Zhuang; Feng Zhou; Yunqin Zhang; Zheng Jin
Journal:  Exp Ther Med       Date:  2018-05-11       Impact factor: 2.447

  7 in total

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