| Literature DB >> 27608546 |
Mohammad G Dekamin1, Elham Kazemi2, Zahra Karimi2, Maryam Mohammadalipoor2, M Reza Naimi-Jamal2.
Abstract
The synergic effect of the chitosan biomacromolecule support for catalyzing of Hantzsch esters formation by CuSO4 has been demonstrated for one-pot and efficient pseudo-four-component reaction to afford a wide range of 1,4-dihydropyridine (DHP) or polyhydroquinoline (PHQ) derivatives. The desired products were simply prepared from different aldehydes, β-dicarbonyls and ammonium acetate in the presence of a low loading of chitosan supported copper(II) sulfate (CSCS) in EtOH under reflux conditions. The biodegradable CSCS catalyst was characterized by field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray spectroscopy analysis (EDX) methods as well as coupled plasma-atomic emission (ICP-AE) and FT-IR spectroscopy. The CSCS catalyst is recyclable and reused four times without significant loss of its activity.Entities:
Keywords: Biodegradable heterogeneous catalysis; Chitosan supported copper(II) sulfate (CSCS); Green chemistry; Hantzsch esters; Multicomponent reactions (MCRs)
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Year: 2016 PMID： 27608546 DOI： 10.1016/j.ijbiomac.2016.09.012
Source DB: PubMed Journal: Int J Biol Macromol ISSN： 0141-8130 Impact factor: 6.953