Literature DB >> 2760822

Ethanol and water sorption into stratum corneum and model systems.

B Berner1, R H Juang, G C Mazzenga.   

Abstract

Sorption of ethanol and water into stratum corneum, delipidized stratum corneum, and triolein as a simple model lipid was investigated. Optima in ethanol sorption and flux are related to dehydration of keratins. There was no optimum for solubility in triolein; a linear cosolvency is observed with ethanol:triolein mixtures. A model is proposed which qualitatively predicts the key features of ethanol-enhanced skin permeation on the basis of these solubility phenomena and a constant diffusion coefficient.

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Year:  1989        PMID： 2760822     DOI： 10.1002/jps.2600780611

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  3 in total

1.  Tracking solvents in the skin through atomically resolved measurements of molecular mobility in intact stratum corneum.

Authors:  Quoc Dat Pham; Daniel Topgaard; Emma Sparr
Journal:  Proc Natl Acad Sci U S A       Date:  2016-12-27       Impact factor: 11.205

2.  An integrated pharmacokinetic and imaging evaluation of vehicle effects on solute human epidermal flux and, retention characteristics.

Authors:  G Winckle; Y G Anissimov; S E Cross; G Wise; M S Roberts
Journal:  Pharm Res       Date:  2007-09-22       Impact factor: 4.200

Review 3.  Dermatologic reactions to disinfectant use during the COVID-19 pandemic.

Authors:  Choon Fu Goh; Long Chiau Ming; Li Ching Wong
Journal:  Clin Dermatol       Date:  2020-10-02       Impact factor: 3.541
  3 in total

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