Literature DB >> 27607909

Pediatric Antipsychotic Use and Outcomes Monitoring.

Paramala J Santosh1,2, Laura Bell1, Federico Fiori1, Jatinder Singh1.   

Abstract

Antipsychotic (ATP) prescription rates have increased in children and adolescents despite concern regarding the safety and effectiveness of ATP usage in community populations. Rising safety concerns and uncertainty regarding ATP effectiveness in children stress the need for improvement in routine clinical outcome monitoring and research. Due to the growing number of children exposed to atypical ATPs, studies assessing the risk/benefit ratio of administering ATPs in this age group-especially in off-label conditions-become of high importance. The Centre for Interventional Pediatric Psychopharmacology and Rare Diseases (CIPPRD) uses a suite of instruments to monitor outcomes using the web-based HealthTracker™, a health monitoring platform. The HealthTracker allows for capture of symptoms, side effects, quality of life, patient experience, and lifetime response to individualized treatments using a multi-informant multimodal methodology. It enables the tracking of ongoing medical treatments and assists in shared treatment decision-making, longitudinal patient centered outcome monitoring, and helps optimize care. An example of its use in the CIPPRD is provided to demonstrate how it can be used for ATP-related outcome monitoring in complex neurodisability within routine clinical practice.

Entities:  

Keywords:  CIPPRD; antipsychotics; children; monitoring; side effects

Mesh:

Substances:

Year:  2016        PMID: 27607909     DOI: 10.1089/cap.2015.0247

Source DB:  PubMed          Journal:  J Child Adolesc Psychopharmacol        ISSN: 1044-5463            Impact factor:   2.576


  8 in total

1.  Autonomic dysfunction and sudden death in patients with Rett syndrome: a systematic review

Authors:  Jatinder Singh; Evamaria Lanzarini; Paramala Santosh
Journal:  J Psychiatry Neurosci       Date:  2020-05-01       Impact factor: 6.186

2.  Patterns of Early Mental Health Diagnosis and Medication Treatment in a Medicaid-Insured Birth Cohort.

Authors:  Dinci Pennap; Julie M Zito; Paramala J Santosh; Sarah E Tom; Eberechukwu Onukwugha; Laurence S Magder
Journal:  JAMA Pediatr       Date:  2018-06-01       Impact factor: 16.193

3.  Paradoxical physiological responses to propranolol in a Rett syndrome patient: a case report.

Authors:  P J Santosh; L Bell; K Lievesley; J Singh; F Fiori
Journal:  BMC Pediatr       Date:  2016-11-29       Impact factor: 2.125

4.  Development of the Tailored Rett Intervention and Assessment Longitudinal (TRIAL) database and the Rett Evaluation of Symptoms and Treatments (REST) Questionnaire.

Authors:  Paramala Santosh; Kate Lievesley; Federico Fiori; Jatinder Singh
Journal:  BMJ Open       Date:  2017-06-21       Impact factor: 2.692

Review 5.  Key issues in Rett syndrome: emotional, behavioural and autonomic dysregulation (EBAD) - a target for clinical trials.

Authors:  Jatinder Singh; Paramala Santosh
Journal:  Orphanet J Rare Dis       Date:  2018-07-31       Impact factor: 4.123

Review 6.  The Burden of Antipsychotic-Induced Weight Gain and Metabolic Syndrome in Children.

Authors:  Mark R Libowitz; Erika L Nurmi
Journal:  Front Psychiatry       Date:  2021-03-12       Impact factor: 4.157

7.  [Research Progress of Antitumor Pharmacovigilance].

Authors:  Wenjuan Sun; Yang Hu; Yan Xu; Bo Zhang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2022-07-20

Review 8.  Propranolol versus Other Selected Drugs in the Treatment of Various Types of Anxiety or Stress, with Particular Reference to Stage Fright and Post-Traumatic Stress Disorder.

Authors:  Łukasz Szeleszczuk; Dawid Frączkowski
Journal:  Int J Mol Sci       Date:  2022-09-03       Impact factor: 6.208

  8 in total

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