Literature DB >> 27605686

Hyaluronic Acid Injections for Treatment of Advanced Osteoarthritis of the Knee: Utilization and Cost in a National Population Sample.

Jack W Weick1, Harpreet S Bawa1, Douglas R Dirschl1.   

Abstract

BACKGROUND: The prevalence of knee osteoarthritis is increasing in the aging U.S. POPULATION: The efficacy and cost-effectiveness of the use of hyaluronic acid (HA) injections for the treatment of knee osteoarthritis are debated. In this study, we assessed the utilization and costs of HA injections in the 12 months preceding total knee arthroplasty (TKA) and evaluated the usage of HA injections in end-stage knee osteoarthritis management in relation to other treatments.
METHODS: MarketScan Commercial Claims and Encounters and Medicare Supplemental and Coordination of Benefits databases (Truven Health Analytics) were reviewed to identify patients who underwent TKA from 2005 to 2012. The utilization of patient-specific osteoarthritis-related health care (including medications, corticosteroid injections, HA injections, imaging, and office visits) and payment information were analyzed for the 12 months preceding TKA.
RESULTS: A total of 244,059 patients met the inclusion criteria. Of those, 35,935 (14.7%) had ≥1 HA injection in the 12 months preceding TKA. HA injections were responsible for 16.4% of all knee osteoarthritis-related payments, trailing only imaging studies (18.2%), and HA injections accounted for 25.2% of treatment-specific payments, a rate that was higher than that of any other treatment. Patients receiving HA injections were significantly more likely to receive additional knee osteoarthritis-related treatments compared with patients who did not receive HA injections.
CONCLUSIONS: Despite numerous studies questioning the efficacy and cost-effectiveness of HA injections for osteoarthritis of the knee, HA injections are still utilized for a substantial percentage of patients. Given the paucity of data supporting the effectiveness of HA injections and the current cost-conscious health-care climate, decreasing their use among patients with end-stage knee osteoarthritis may represent a substantial cost reduction that likely does not adversely impact the quality of care.
Copyright © 2016 by The Journal of Bone and Joint Surgery, Incorporated.

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Year:  2016        PMID: 27605686     DOI: 10.2106/JBJS.15.01358

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  12 in total

1.  The effect of hyaluronic acid on the corrosion of an orthopedic CoCrMo-alloy in simulated inflammatory conditions.

Authors:  S Radice; J Yao; J Babauta; M P Laurent; M A Wimmer
Journal:  Materialia (Oxf)       Date:  2019-05-10

Review 2.  Knee Osteoarthritis: A Primer.

Authors:  Michelle J Lespasio; Nicolas S Piuzzi; M Elaine Husni; George F Muschler; Aj Guarino; Michael A Mont
Journal:  Perm J       Date:  2017

3.  Hyaluronic acid injections for osteoarthritis of the knee: predictors of successful treatment.

Authors:  Eric N Bowman; Justin D Hallock; Thomas W Throckmorton; Fredrick M Azar
Journal:  Int Orthop       Date:  2018-01-03       Impact factor: 3.075

Review 4.  Osteoarthritis year in review 2017: clinical.

Authors:  A E Nelson
Journal:  Osteoarthritis Cartilage       Date:  2017-12-08       Impact factor: 6.576

5.  Viscosupplementation in patients with severe osteoarthritis of the knee: six month follow-up of a randomized, double-blind clinical trial.

Authors:  André Luiz Siqueira Campos; Rodrigo Satamini Pires E Albuquerque; Edmilson Barbosa da Silva; Sami Gobbi Fayad; Lucas Delunardo Acerbi; Felipe Nunes de Almeida; Nelson Hiroyuki Myiabe Ooka; José Sergio Franco; Vinícius Schott Gameiro
Journal:  Int Orthop       Date:  2017-08-30       Impact factor: 3.075

6.  Cost-of-illness of knee osteoarthritis: potential cost savings by not undergoing arthroplasty within the first 2 years.

Authors:  Kevin L Ong; Maria Runa; Edmund Lau; Roy D Altman
Journal:  Clinicoecon Outcomes Res       Date:  2019-03-14

Review 7.  Intra-articular Hyaluronic Acid for Osteoarthritis of the Knee in the United States: A Systematic Review of Economic Evaluations.

Authors:  Margaret Mordin; William Parrish; Catherine Masaquel; Brad Bisson; Catherine Copley-Merriman
Journal:  Clin Med Insights Arthritis Musculoskelet Disord       Date:  2021-11-19

8.  Value-Based Care for Nonoperative Management of Hip and Knee Osteoarthritis: Current Landscape Not Ripe for Implementation.

Authors:  Kelly R Stiegel; Melvyn A Harrington; Mohamad J Halawi
Journal:  Arthroplast Today       Date:  2021-05-15

9.  Knee OA cost comparison for hyaluronic acid and knee arthroplasty.

Authors:  Kevin L Ong; Faizan Niazi; Edmund Lau; Michael A Mont; Andrew Concoff; Peter Shaw; Steven M Kurtz
Journal:  J Orthop Surg Res       Date:  2020-08-06       Impact factor: 2.359

Review 10.  Hyaluronic Acid Injections or Oral Nonsteroidal Anti-inflammatory Drugs for Knee Osteoarthritis: Systematic Review and Meta-analysis of Randomized Trials.

Authors:  Larry E Miller; Michael Fredericson; Roy D Altman
Journal:  Orthop J Sports Med       Date:  2020-01-27
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