Literature DB >> 27605263

A lysosome-targeted fluorescent sensor for the detection of glutathione in cells with an extremely fast response.

Rong Huang1, Bei-Bei Wang, Xing-Ming Si-Tu, Tao Gao, Fang-Fang Wang, Huan He, Xiao-Yang Fan, Feng-Lei Jiang, Yi Liu.   

Abstract

A highly sensitive and selective Rhodamine B-based fluorescent sensor, RhB-1, for glutathione (GSH) was easily synthesized. An extremely fast detection response time of 10 s, which is the fastest one ever reported, is achieved in aqueous solutions over a wide pH range with large enhancement of emission intensity. The sensor detects GSH in cells and selectively accumulates in lysosomes.

Entities:  

Year:  2016        PMID： 27605263     DOI： 10.1039/c6cc06750f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

Review 1.  Fluorescent probes for organelle-targeted bioactive species imaging.

Authors:  Peng Gao; Wei Pan; Na Li; Bo Tang
Journal:  Chem Sci       Date:  2019-05-24       Impact factor: 9.825

2.  Naphthalene-based fluorescent probes for glutathione and their applications in living cells and patients with sepsis.

Authors:  Jun Li; Younghee Kwon; Kyung Soo Chung; Chang Su Lim; Dayoung Lee; Yongkang Yue; Jisoo Yoon; Gyoungmi Kim; Sang-Jip Nam; Youn Wook Chung; Hwan Myung Kim; Caixia Yin; Ji-Hwan Ryu; Juyoung Yoon
Journal:  Theranostics       Date:  2018-02-03       Impact factor: 11.556

Review 3.  Stimuli-responsive prodrug-based cancer nanomedicine.

Authors:  Angel Xie; Sumaira Hanif; Jiang Ouyang; Zhongmin Tang; Na Kong; Na Yoon Kim; Baowen Qi; Dylan Patel; Bingyang Shi; Wei Tao
Journal:  EBioMedicine       Date:  2020-06-07       Impact factor: 8.143

4.  A GSH Fluorescent Probe with a Large Stokes Shift and Its Application in Living Cells.

Authors:  Yueyuan Mao; Yediao Xu; Zhi Li; Yang Wang; Huanhuan Du; Lei Liu; Ran Ding; Guodong Liu
Journal:  Sensors (Basel)       Date:  2019-12-04       Impact factor: 3.576
  4 in total

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