Literature DB >> 27604694

Correction: High-throughput screening for modulators of ACVR1 transcription: discovery of potential therapeutics for fibrodysplasia ossificans progressiva.

Serena Cappato, Laura Tonachini, Francesca Giacopelli, Mario Tirone, Luis J V Galietta, Martina Sormani, Anna Giovenzana, Antonello E Spinelli, Barbara Canciani, Silvia Brunelli, Roberto Ravazzolo, Renata Bocciardi.   

Abstract

Entities:  

Year:  2016        PMID: 27604694      PMCID: PMC5047694          DOI: 10.1242/dmm.027573

Source DB:  PubMed          Journal:  Dis Model Mech        ISSN: 1754-8403            Impact factor:   5.758


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There was an error concerning Fig. 4 in Dis. Model. Mech. 9, 685-696.
Fig. 4.

Effect of Dipy on the expression of chondrogenic markers. RT-qPCR on RNA extracted from ATDC5 cells cultured as alginate spheres for 14 days in differentiation medium. Bars show mean and s.d. of three independent experiments. Expression levels were normalized on GAPDH and 18S and compared to that of cells at T0 (cells harvested at the beginning of the differentiation protocol). Un, untreated cells. ns, non-significant; *P<0.05, §P<0.001.

The wrong figure was used for Fig. 4. The correct figure is shown in this Correction with its legend. The PDF and full-text version of this article have been corrected. Effect of Dipy on the expression of chondrogenic markers. RT-qPCR on RNA extracted from ATDC5 cells cultured as alginate spheres for 14 days in differentiation medium. Bars show mean and s.d. of three independent experiments. Expression levels were normalized on GAPDH and 18S and compared to that of cells at T0 (cells harvested at the beginning of the differentiation protocol). Un, untreated cells. ns, non-significant; *P<0.05, §P<0.001. The authors and DMM office apologise to the readers for this error.
  2 in total

1.  AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of osteogenic differentiation.

Authors:  Hui Lin; Ying Ying; Yuan-Yuan Wang; Gang Wang; Shan-Shan Jiang; Deqinag Huang; Lingyu Luo; Ye-Guang Chen; Louis C Gerstenfeld; Zhijun Luo
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2017-08-25       Impact factor: 4.739

2.  Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells.

Authors:  Gonzalo Sánchez-Duffhues; Eleanor Williams; Pascal Benderitter; Valeria Orlova; Michiel van Wijhe; Amaya Garcia de Vinuesa; Georgina Kerr; Josselin Caradec; Kirsten Lodder; Hetty C de Boer; Marie-José Goumans; Elisabeth M W Eekhoff; Antonio Morales-Piga; Javier Bachiller-Corral; Pieter Koolwijk; Alex N Bullock; Jan Hoflack; Peter Ten Dijke
Journal:  JBMR Plus       Date:  2019-10-07
  2 in total

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