Literature DB >> 27604646

Single-armed phenylsulfonated pyridine derivative of DOTA is rigid and stable paramagnetic tag in protein analysis.

Feng Yang1, Xiao Wang, Bin-Bin Pan, Xun-Cheng Su.   

Abstract

Single-armed DOTA-like phenylsulfonated pyridine derivatives are rigid and stable paramagnetic tags for site-specific labeling of proteins. Their reactions with a solvent-exposed protein thiol group generate a stable C-S bond and produce one single paramagnetic species in solution NMR. The generated large paramagnetic effects yield valuable long-range structural restraints for proteins.

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Year:  2016        PMID: 27604646     DOI: 10.1039/c6cc06114a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  5 in total

Review 1.  Characterizing conformational ensembles of multi-domain proteins using anisotropic paramagnetic NMR restraints.

Authors:  Xue-Ni Hou; Hidehito Tochio
Journal:  Biophys Rev       Date:  2022-01-11

2.  Characterizing the magnetic susceptibility tensor of lanthanide-containing polymethylated-DOTA complexes.

Authors:  Madeleine Strickland; Charles D Schwieters; Christoph Göbl; Ana C L Opina; Marie-Paule Strub; Rolf E Swenson; Olga Vasalatiy; Nico Tjandra
Journal:  J Biomol NMR       Date:  2016-09-22       Impact factor: 2.835

Review 3.  A Double-Armed, Hydrophilic Transition Metal Complex as a Paramagnetic NMR Probe.

Authors:  Qing Miao; Wei-Min Liu; Thomas Kock; Anneloes Blok; Monika Timmer; Mark Overhand; Marcellus Ubbink
Journal:  Angew Chem Int Ed Engl       Date:  2019-08-13       Impact factor: 15.336

4.  The Photocatalyzed Thiol-ene reaction: A New Tag to Yield Fast, Selective and reversible Paramagnetic Tagging of Proteins.

Authors:  Maxime Denis; Charlotte Softley; Stefano Giuntini; Matteo Gentili; Enrico Ravera; Giacomo Parigi; Marco Fragai; Grzegorz Popowicz; Michael Sattler; Claudio Luchinat; Linda Cerofolini; Cristina Nativi
Journal:  Chemphyschem       Date:  2020-03-19       Impact factor: 3.102

5.  A Two-Armed Probe for In-Cell DEER Measurements on Proteins*.

Authors:  Qing Miao; Enrico Zurlo; Donny de Bruin; Joeri A J Wondergem; Monika Timmer; Anneloes Blok; Doris Heinrich; Mark Overhand; Martina Huber; Marcellus Ubbink
Journal:  Chemistry       Date:  2020-11-17       Impact factor: 5.236

  5 in total

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