| Literature DB >> 27604646 |
Feng Yang1, Xiao Wang, Bin-Bin Pan, Xun-Cheng Su.
Abstract
Single-armed DOTA-like phenylsulfonated pyridine derivatives are rigid and stable paramagnetic tags for site-specific labeling of proteins. Their reactions with a solvent-exposed protein thiol group generate a stable C-S bond and produce one single paramagnetic species in solution NMR. The generated large paramagnetic effects yield valuable long-range structural restraints for proteins.Entities:
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Year: 2016 PMID: 27604646 DOI: 10.1039/c6cc06114a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222