Literature DB >> 27604289

Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives.

Torsten Busch1, Gerald Dräger, Eike Kunst, Hannah Benson, Florenz Sasse, Karsten Siems, Andreas Kirschning.   

Abstract

The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 27604289     DOI： 10.1039/c6ob01697a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  6 in total

Review 1.  Treasure troves of pharmacological tools to study transient receptor potential canonical 1/4/5 channels.

Authors:  Hussein N Rubaiy
Journal:  Br J Pharmacol       Date:  2019-03-06       Impact factor: 8.739

2.  Antitumor and antiangiogenic effects of Tonantzitlolone B, an uncommon diterpene from Stillingia loranthacea.

Authors:  Renata A de Abrantes; Tatianne M Batista; Vivianne M Mangueira; Tatyanna K G de Sousa; Rafael C Ferreira; Ana Paula G Moura; Lucas S Abreu; Adriano F Alves; Eudes S Velozo; Leônia M Batista; Marcelo S da Silva; Josean F Tavares; Marianna V Sobral
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2021-12-02       Impact factor: 3.000

Review 3.  Phytochemicals for the Prevention and Treatment of Renal Cell Carcinoma: Preclinical and Clinical Evidence and Molecular Mechanisms.

Authors:  Essa M Bajalia; Farah B Azzouz; Danielle A Chism; Derrek M Giansiracusa; Carina G Wong; Kristina N Plaskett; Anupam Bishayee
Journal:  Cancers (Basel)       Date:  2022-07-04       Impact factor: 6.575

4.  Tailoring chemoenzymatic oxidation via in situ peracids.

Authors:  Rebecca N Re; Johanna C Proessdorf; James J La Clair; Maeva Subileau; Michael D Burkart
Journal:  Org Biomol Chem       Date:  2019-11-06       Impact factor: 3.876

5.  Tonantzitlolone is a nanomolar potency activator of transient receptor potential canonical 1/4/5 channels.

Authors:  Hussein N Rubaiy; Melanie J Ludlow; Karsten Siems; Katherine Norman; Richard Foster; Dietmar Wolf; John A Beutler; David J Beech
Journal:  Br J Pharmacol       Date:  2018-06-28       Impact factor: 8.739

Review 6.  Canonical transient receptor potential channels and their modulators: biology, pharmacology and therapeutic potentials.

Authors:  Yuan-Yuan Gao; Wen Tian; Hui-Nan Zhang; Yang Sun; Jing-Ru Meng; Wei Cao; Xiao-Qiang Li
Journal:  Arch Pharm Res       Date:  2021-03-24       Impact factor: 4.946
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.