Literature DB >> 27603130

Dysregulated exocytosis of angiopoietin-2 drives cerebral cavernous malformation.

Helong Zhao1, Tara M Mleynek1, Dean Y Li2.   

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Year:  2016        PMID： 27603130     DOI： 10.1038/nm.4178

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  11 in total

1.  Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.

Authors:  Aubrey C Chan; Stavros G Drakos; Oscar E Ruiz; Alexandra C H Smith; Christopher C Gibson; Jing Ling; Samuel F Passi; Amber N Stratman; Anastasia Sacharidou; M Patricia Revelo; Allie H Grossmann; Nikolaos A Diakos; George E Davis; Mark M Metzstein; Kevin J Whitehead; Dean Y Li
Journal:  J Clin Invest       Date:  2011-04-01       Impact factor: 14.808

Review 2.  Genetics of cerebral cavernous malformations.

Authors:  Nicholas W Plummer; Jon S Zawistowski; Douglas A Marchuk
Journal:  Curr Neurol Neurosci Rep       Date:  2005-09       Impact factor: 5.081

Review 3.  Cerebral cavernous malformation proteins at a glance.

Authors:  Kyle M Draheim; Oriana S Fisher; Titus J Boggon; David A Calderwood
Journal:  J Cell Sci       Date:  2014-01-30       Impact factor: 5.285

4.  Ultrastructural and immunocytochemical evidence that an incompetent blood-brain barrier is related to the pathophysiology of cavernous malformations.

Authors:  R E Clatterbuck; C G Eberhart; B J Crain; D Rigamonti
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-08       Impact factor: 10.154

5.  EndMT contributes to the onset and progression of cerebral cavernous malformations.

Authors:  Luigi Maddaluno; Noemi Rudini; Roberto Cuttano; Luca Bravi; Costanza Giampietro; Monica Corada; Luca Ferrarini; Fabrizio Orsenigo; Eleanna Papa; Gwenola Boulday; Elisabeth Tournier-Lasserve; Françoise Chapon; Cristina Richichi; Saverio Francesco Retta; Maria Grazia Lampugnani; Elisabetta Dejana
Journal:  Nature       Date:  2013-06-09       Impact factor: 49.962

6.  Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.

Authors:  Christopher C Gibson; Weiquan Zhu; Chadwick T Davis; Jay A Bowman-Kirigin; Aubrey C Chan; Jing Ling; Ashley E Walker; Luca Goitre; Simona Delle Monache; Saverio Francesco Retta; Yan-Ting E Shiu; Allie H Grossmann; Kirk R Thomas; Anthony J Donato; Lisa A Lesniewski; Kevin J Whitehead; Dean Y Li
Journal:  Circulation       Date:  2014-12-08       Impact factor: 29.690

7.  The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies.

Authors:  Ulrike Fiedler; Marion Scharpfenecker; Stefanie Koidl; Anja Hegen; Verena Grunow; Jarno M Schmidt; Wilhelm Kriz; Gavin Thurston; Hellmut G Augustin
Journal:  Blood       Date:  2004-02-19       Impact factor: 22.113

8.  The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases.

Authors:  Kevin J Whitehead; Aubrey C Chan; Sutip Navankasattusas; Wonshill Koh; Nyall R London; Jing Ling; Anne H Mayo; Stavros G Drakos; Christopher A Jones; Weiquan Zhu; Douglas A Marchuk; George E Davis; Dean Y Li
Journal:  Nat Med       Date:  2009-01-18       Impact factor: 53.440

9.  Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling.

Authors:  Zinan Zhou; Alan T Tang; Weng-Yew Wong; Sharika Bamezai; Lauren M Goddard; Robert Shenkar; Su Zhou; Jisheng Yang; Alexander C Wright; Matthew Foley; J Simon C Arthur; Kevin J Whitehead; Issam A Awad; Dean Y Li; Xiangjian Zheng; Mark L Kahn
Journal:  Nature       Date:  2016-03-30       Impact factor: 49.962

10.  Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation.

Authors:  Huanjiao Jenny Zhou; Lingfeng Qin; Haifeng Zhang; Wenwen Tang; Weidong Ji; Yun He; Xiaoling Liang; Zongren Wang; Qianying Yuan; Alexander Vortmeyer; Derek Toomre; Germaine Fuh; Minghong Yan; Martin S Kluger; Dianqing Wu; Wang Min
Journal:  Nat Med       Date:  2016-08-22       Impact factor: 53.440
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  2 in total

Review 1.  Molecular Genetic Features of Cerebral Cavernous Malformations (CCM) Patients: An Overall View from Genes to Endothelial Cells.

Authors:  Giulia Riolo; Claudia Ricci; Stefania Battistini
Journal:  Cells       Date:  2021-03-22       Impact factor: 6.600

2.  Signalling through cerebral cavernous malformation protein networks.

Authors:  Valerie L Su; David A Calderwood
Journal:  Open Biol       Date:  2020-11-25       Impact factor: 6.411
  2 in total

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