Literature DB >> 27602408

Smartphone Operated Signal Transduction by Ion Nanogating (STING) Amplifier for Nanopore Sensors: Design and Analytical Application.

Rıfat Emrah Özel1, Sina Kahnemouyi2, Hsinwen Fan1, Wai Han Mak1, Akshar Lohith1, Adam Seger1, Mircea Teodorescu2, Nader Pourmand1.   

Abstract

In this report, we demonstrated a handheld wireless voltage-clamp amplifier for current measurement of nanopore sensors. This amplifier interfaces a sensing probe and connects wirelessly with a computer or smartphone for the required stimulus input, data processing and storage. To test the proposed Signal Transduction by Ion Nanogating (STING) wireless amplifier, in the current study the system was tested with a nano-pH sensor to measure pH of standard buffer solutions and the performance was compared against the commercial voltage-clamp amplifier. To our best knowledge, STING amplifier is the first miniaturized wireless voltage-clamp platform operated with a customized smart-phone application (app).

Entities:  

Keywords:  Biosensor; Ionic Conductance; Low noise; Miniaturized sensing device; Nanopipette; Point-of-care; Portable instrumentation; Voltage-clamp

Year:  2016        PMID: 27602408      PMCID: PMC5010862          DOI: 10.1021/acssensors.5b00289

Source DB:  PubMed          Journal:  ACS Sens        ISSN: 2379-3694            Impact factor:   7.711


  14 in total

1.  High-throughput screening for ion channel modulators.

Authors:  Margaret Falconer; Fiona Smith; Sandha Surah-Narwal; Gill Congrave; Zhen Liu; Paul Hayter; Giuseppe Ciaramella; Wilma Keighley; Peter Haddock; Gareth Waldron; Andreas Sewing
Journal:  J Biomol Screen       Date:  2002-10

Review 2.  Immobilization strategies to develop enzymatic biosensors.

Authors:  Audrey Sassolas; Loïc J Blum; Béatrice D Leca-Bouvier
Journal:  Biotechnol Adv       Date:  2011-09-17       Impact factor: 14.227

3.  Label-free biosensing with functionalized nanopipette probes.

Authors:  Senkei Umehara; Miloslav Karhanek; Ronald W Davis; Nader Pourmand
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-05       Impact factor: 11.205

4.  CMOS low current measurement system for biomedical applications.

Authors:  Brian Goldstein; Dongsoo Kim; Jian Xu; T Kyle Vanderlick; Eugenio Culurciello
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2012-04       Impact factor: 3.833

5.  Improved ion-selective detection method using nanopipette with poly(vinyl chloride)-based membrane.

Authors:  Eun Ji Kang; Tomohide Takami; Xiao Long Deng; Jong Wan Son; Tomoji Kawai; Bae Ho Park
Journal:  J Phys Chem B       Date:  2014-05-01       Impact factor: 2.991

Review 6.  Immobilization of histidine-tagged proteins on electrodes.

Authors:  Claudia Ley; Dirk Holtmann; Klaus-Michael Mangold; Jens Schrader
Journal:  Colloids Surf B Biointerfaces       Date:  2011-07-26       Impact factor: 5.268

7.  Integrated nanopore sensing platform with sub-microsecond temporal resolution.

Authors:  Jacob K Rosenstein; Meni Wanunu; Christopher A Merchant; Marija Drndic; Kenneth L Shepard
Journal:  Nat Methods       Date:  2012-03-18       Impact factor: 28.547

Review 8.  Noise limits of CMOS current interfaces for biosensors: a review.

Authors:  Marco Crescentini; Marco Bennati; Marco Carminati; Marco Tartagni
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2014-04       Impact factor: 3.833

9.  RECENT DEVELOPMENTS IN ELECTROCHEMICAL SENSORS FOR THE DETECTION OF NEUROTRANSMITTERS FOR APPLICATIONS IN BIOMEDICINE.

Authors:  Rıfat Emrah Özel; Akhtar Hayat; Silvana Andreescu
Journal:  Anal Lett       Date:  2014-12-31       Impact factor: 2.329

10.  Functionalized nanopipettes: toward label-free, single cell biosensors.

Authors:  Paolo Actis; Andy C Mak; Nader Pourmand
Journal:  Bioanal Rev       Date:  2010-06-19
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  1 in total

1.  Bioinspired integrated nanosystems based on solid-state nanopores: "iontronic" transduction of biological, chemical and physical stimuli.

Authors:  Gonzalo Pérez-Mitta; Alberto G Albesa; Christina Trautmann; María Eugenia Toimil-Molares; Omar Azzaroni
Journal:  Chem Sci       Date:  2016-10-26       Impact factor: 9.825

  1 in total

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