Literature DB >> 27599536

Alzheimer's disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide.

Deepak Kumar Vijaya Kumar1, William A Eimer1, Rudolph E Tanzi1, Robert D Moir1.   

Abstract

Entities:  

Keywords:  Alzheimer's disease; amyloid-β; infection

Mesh：

Substances：

Year:  2016        PMID： 27599536      PMCID： PMC5558531          DOI： 10.2217/nmt-2016-0035

Source DB:  PubMed          Journal:  Neurodegener Dis Manag        ISSN： 1758-2024


× No keyword cloud information.
  19 in total

1.  Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism.

Authors:  D Paris; T Town; T A Parker; J Tan; J Humphrey; F Crawford; M Mullan
Journal:  Exp Neurol       Date:  1999-05       Impact factor: 5.330

2.  Paradise lost and paradigm found.

Authors:  Robert I Lehrer
Journal:  Nat Immunol       Date:  2004-08       Impact factor: 25.606

Review 3.  Evolution of innate and adaptive immunity: can we draw a line?

Authors:  Martin F Flajnik; Louis Du Pasquier
Journal:  Trends Immunol       Date:  2004-12       Impact factor: 16.687

4.  A folding-dependent mechanism of antimicrobial peptide resistance to degradation unveiled by solution structure of distinctin.

Authors:  Domenico Raimondo; Giuseppina Andreotti; Nathalie Saint; Pietro Amodeo; Giovanni Renzone; Marina Sanseverino; Ivana Zocchi; Gerard Molle; Andrea Motta; Andrea Scaloni
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-19       Impact factor: 11.205

Review 5.  Host defense peptides: front-line immunomodulators.

Authors:  Sarah C Mansour; Olga M Pena; Robert E W Hancock
Journal:  Trends Immunol       Date:  2014-08-08       Impact factor: 16.687

Review 6.  Antimicrobial peptides: the ancient arm of the human immune system.

Authors:  Jochen Wiesner; Andreas Vilcinskas
Journal:  Virulence       Date:  2010 Sep-Oct       Impact factor: 5.882

7.  Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity.

Authors:  Z Oren; J C Lerman; G H Gudmundsson; B Agerberth; Y Shai
Journal:  Biochem J       Date:  1999-08-01       Impact factor: 3.857

8.  Amyloid-β oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodies.

Authors:  Malin Lindhagen-Persson; Kristoffer Brännström; Monika Vestling; Michael Steinitz; Anders Olofsson
Journal:  PLoS One       Date:  2010-11-10       Impact factor: 3.240

9.  Binding of LL-37 to model biomembranes: insight into target vs host cell recognition.

Authors:  Rohit Sood; Yegor Domanov; Milla Pietiäinen; Vesa P Kontinen; Paavo K J Kinnunen
Journal:  Biochim Biophys Acta       Date:  2007-12-14

10.  Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease.

Authors:  Deepak Kumar Vijaya Kumar; Se Hoon Choi; Kevin J Washicosky; William A Eimer; Stephanie Tucker; Jessica Ghofrani; Aaron Lefkowitz; Gawain McColl; Lee E Goldstein; Rudolph E Tanzi; Robert D Moir
Journal:  Sci Transl Med       Date:  2016-05-25       Impact factor: 17.956
View more
  17 in total

1.  A long-lived Aβ oligomer resistant to fibrillization.

Authors:  Mimi Nick; Yibing Wu; Nathan W Schmidt; Stanley B Prusiner; Jan Stöhr; William F DeGrado
Journal:  Biopolymers       Date:  2018-01-10       Impact factor: 2.505

Review 2.  Peptoid drug discovery and optimization via surface X-ray scattering.

Authors:  Konstantin Andreev; Michael W Martynowycz; David Gidalevitz
Journal:  Biopolymers       Date:  2019-03-20       Impact factor: 2.505

3.  Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression.

Authors:  Xue Chen; Suixin Deng; Wenchao Wang; Stefania Castiglione; Zilei Duan; Lei Luo; Francesca Cianci; Xiaoxue Zhang; Jianglei Xu; Hao Li; Jizong Zhao; Peter Muiruri Kamau; Zhiye Zhang; James Mwangi; Jiali Li; Yousheng Shu; Xintian Hu; Michele Mazzanti; Ren Lai
Journal:  Mol Psychiatry       Date:  2022-09-22       Impact factor: 13.437

Review 4.  Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer's Disease.

Authors:  Tamas Fulop; Shreyansh Tripathi; Serafim Rodrigues; Mathieu Desroches; Ton Bunt; Arnold Eiser; Francois Bernier; Pascale B Beauregard; Annelise E Barron; Abdelouahed Khalil; Adam Plotka; Katsuiku Hirokawa; Anis Larbi; Christian Bocti; Benoit Laurent; Eric H Frost; Jacek M Witkowski
Journal:  Neuropsychiatr Dis Treat       Date:  2021-05-04       Impact factor: 2.570

Review 5.  γ-Secretase in Alzheimer's disease.

Authors:  Ji-Yeun Hur
Journal:  Exp Mol Med       Date:  2022-04-08       Impact factor: 12.153

6.  Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer's Disease.

Authors:  Tamàs Fülöp; Usma Munawara; Anis Larbi; Mathieu Desroches; Serafim Rodrigues; Michele Catanzaro; Andrea Guidolin; Abdelouahed Khalil; François Bernier; Annelise E Barron; Katsuiku Hirokawa; Pascale B Beauregard; David Dumoulin; Jean-Philippe Bellenger; Jacek M Witkowski; Eric Frost
Journal:  CNS Drugs       Date:  2020-07       Impact factor: 6.497

Review 7.  Our (Mother's) Mitochondria and Our Mind.

Authors:  Peter Kramer; Paola Bressan
Journal:  Perspect Psychol Sci       Date:  2017-09-22

8.  Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer's Disease.

Authors:  Amanda L Lumsden; Jack T Rogers; Shohreh Majd; Morgan Newman; Greg T Sutherland; Giuseppe Verdile; Michael Lardelli
Journal:  Front Neurosci       Date:  2018-08-13       Impact factor: 4.677

Review 9.  Supramolecular Peptide Assemblies as Antimicrobial Scaffolds.

Authors:  Andrew W Simonson; Matthew R Aronson; Scott H Medina
Journal:  Molecules       Date:  2020-06-14       Impact factor: 4.411

10.  Potential Virus Involvement in Alzheimer's Disease: Results from a Phase IIa Trial Evaluating Apovir, an Antiviral Drug Combination.

Authors:  Nina Lindblom; Lars Lindquist; Jacob Westman; Mikael Åström; Roger Bullock; Suzanne Hendrix; Lars-Olof Wahlund
Journal:  J Alzheimers Dis Rep       Date:  2021-05-28
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.