| Literature DB >> 27599508 |
A A Kudriaeva1, N A Khaustova2, D V Maltseva2, E S Kuzina1, I S Glagoleva3, E A Surina1, V D Knorre4, A A Belogurov1,3, A G Tonevitsky2, A G Gabibov1,3,5.
Abstract
In this study, we performed transcriptome profiling of oligodendrocyte culture of mice treated with the remyelinating therapeutic agent benztropine in the presence and absence of interferon gamma (IFNγ). The results of this work are important for understanding the expression profile of oligodendrocytes under conditions of systemic inflammation in the central nervous system in multiple sclerosis as well as the mechanisms of cellular response to benztropine in light of its possible use for the treatment of multiple sclerosis.Entities:
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Year: 2016 PMID： 27599508 DOI： 10.1134/S1607672916040086
Source DB: PubMed Journal: Dokl Biochem Biophys ISSN： 1607-6729 Impact factor: 0.788