Rathinam Sivakumar1, Vijayakumar Balakrishnan1, Priya Gowri2, Jeyaseelan Visalakshi3. 1. a Aravind Eye Hospital , Biostatistics , Madurai , India. 2. b Aravind Medical Research Foundation , Madurai , India. 3. c Christian Medical College and Hospital Vellore , Department of Biostatistics , Vellore , India.
Abstract
PURPOSE: To analyze the diagnostic predictive ability of clinical variables. METHODS: Demographic and clinical variables of 172 serologically proven leptospiral uveitis patients were compared with 200 controls of non-leptospiral uveitis. Multiple logistic regression analysis identified diagnostic predictors. A receiver operating characteristic curve tested the performance of the model. RESULTS: Of all variables, male gender, farming as an occupation, and clinical features such as non-granulomatous panuveitis, hypopyon, and vitreous infiltration in the absence of retinochoroiditis constituted the predictive parameters, with the sensitivity and specificity of 86% and 90.7%, respectively. CONCLUSIONS: Multiple logistic analysis detected clinically diagnostic predictors that can assist primary care ophthalmologists. Clinical diagnosis can further be confirmed by serology at tertiary care centers.
PURPOSE: To analyze the diagnostic predictive ability of clinical variables. METHODS: Demographic and clinical variables of 172 serologically proven leptospiral uveitispatients were compared with 200 controls of non-leptospiral uveitis. Multiple logistic regression analysis identified diagnostic predictors. A receiver operating characteristic curve tested the performance of the model. RESULTS: Of all variables, male gender, farming as an occupation, and clinical features such as non-granulomatous panuveitis, hypopyon, and vitreous infiltration in the absence of retinochoroiditis constituted the predictive parameters, with the sensitivity and specificity of 86% and 90.7%, respectively. CONCLUSIONS: Multiple logistic analysis detected clinically diagnostic predictors that can assist primary care ophthalmologists. Clinical diagnosis can further be confirmed by serology at tertiary care centers.