Literature DB >> 27598228

The neutrophil-to-lymphocyte ratio in children with sudden sensorineural hearing loss: a retrospective study.

Joong Seob Lee1, Sung Kwang Hong1, Dong Hyun Kim1, Ju Han Lee1, Hyo-Jeong Lee1, Bumjung Park1, Hyo Geun Choi1, Il Gyu Kong1, Hong Ji Song2,3, Hyung-Jong Kim1.   

Abstract

CONCLUSION: The elevated neutrophil-to-lymphocyte ratio (NLR) value in children with sudden sensorineural hearing loss (SSNHL) would suggest the inflammatory etiology of pediatric SSNHL. The results of this study may suggest NLR value can be used as a useful indicator, which is associated with the disease severity in pediatric SSNHL.
OBJECTIVES: This study aimed to elucidate any clues of inflammatory etiology, which might be related with the development of pediatric SSNHL, using calculated NLR.
METHODS: Forty-six patients aged younger than 19 years, who were admitted to the hospital with the diagnosis of SSNHL, were included in the study. Forty-six healthy children were matched as control group according to their propensity score. The complete blood cell count, calculated NLR, platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) were compared. The relationship between NLR and the initial hearing level was also investigated.
RESULTS: The mean NLR value was 2.86 ± 2.58 in the SSNHL group, whereas the mean NLR value was 1.63 ± 0.87 in the control group. The mean NLR value of the SSNHL children was significantly higher than that of the control group (p = .023). There was a positive correlation between the NLR value and initial hearing level (r = .312, p = .037).

Entities:  

Keywords:  Neutrophil-to-lymphocyte ratio; children; sudden deafness

Mesh:

Year:  2016        PMID: 27598228     DOI: 10.1080/00016489.2016.1217561

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  5 in total

1.  Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Patients with Sudden Sensorineural Hearing Loss.

Authors:  Xiao-Feng Qiao; Xin Li; Guo-Ping Wang; Yin-Huan Bai; Wei Zheng; Tong-Li Li
Journal:  Med Princ Pract       Date:  2018-10-16       Impact factor: 1.927

2.  Relationship between platelet parameters and sudden sensorineural hearing loss: a systematic review and meta-analysis.

Authors:  Shuaifei Ji; Xuemin Chen; Heng Shi; Babo Zhang; Shun Yao; Senlin Deng; Chunlong Tian; Jun Jiang; Fei Chen; Xiaocheng Wang
Journal:  Biosci Rep       Date:  2018-11-13       Impact factor: 3.840

Review 3.  Neutrophil-to-lymphocyte ratio predicts diagnosis and prognosis of idiopathic sudden sensorineural hearing loss: A systematic review and meta-analysis.

Authors:  Liquan Chen; Gaohua Zhang; Zhanhui Zhang; Yufeng Wang; Liren Hu; Jiayuan Wu
Journal:  Medicine (Baltimore)       Date:  2018-09       Impact factor: 1.817

Review 4.  Association between routine hematological parameters and sudden sensorineural hearing loss: A meta-analysis.

Authors:  Wei Ni; Shao-Peng Song; Yi-Dao Jiang
Journal:  J Otol       Date:  2020-08-09

5.  Correlation of Neutrophil-to-Lymphocyte Ratio and the Dilation of the Basilar Artery with the Potential Role of Vascular Compromise in the Pathophysiology of Idiopathic Sudden Sensorineural Hearing Loss.

Authors:  Dae-Woong Kang; Seul Kim; Woongsang Sunwoo
Journal:  J Clin Med       Date:  2022-10-08       Impact factor: 4.964

  5 in total

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