| Literature DB >> 27595830 |
L B Korolevskaya1,2, K V Shmagel3,4, E V Saidakova3,4, N G Shmagel4,5, V A Chereshnev4,6.
Abstract
Uninfected donor T cells were treated in vitro by model immune complexes that contained either HIV or hepatitis C virus (HCV) antigens. Unlike HCV antigen-containing complexes, the immune complexes that contained HIV antigens have been shown to activate peripheral blood T cells of uninfected donors under in vitro conditions. Both the antiviral antibodies and HIV antigen were involved in the activation process. The unique properties of the immune complexes formed by HIV antigens and antiviral antibodies are believed to result from the virus-specific antibody properties and molecular conformation of the antigen-antibody complex.Entities:
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Year: 2016 PMID： 27595830 DOI： 10.1134/S0012496616040062
Source DB: PubMed Journal: Dokl Biol Sci ISSN： 0012-4966