Marisela Castro-Ibarra1, Rufino Menchaca-Díaz2, J Jesús Cabrales-Ruvalcaba2, Rosa Alicia Luna-V Gómez1. 1. Instituto de Seguridad y Servicios Sociales de los Trabajadores del Gobierno y Municipios del Estado de Baja California (ISSSTECALI), Tijuana, Baja California, México. 2. Salud Pública, Facultad de Medicina y Psicología, Universidad Autónoma de Baja California campus Tijuana, Tijuana, Baja California, México.
Abstract
OBJECTIVE: To analyze the association between a false positive result in mammography and obesity, inside the breast cancer early detection program in women affiliated to the Institute of Security and Social Services for Government and Municipality workers of the State of Baja California (ISSSTECALI). MATERIAL AND METHODS: A case-control, retrospective study was done in women affiliated to ISSSTECALI to whom a mammography was performed between 2009 and 2012. Women with a false positive result in mammography were included as cases. Controls were women with a true negative result in mammography. Three controls were randomly selected for each case. Obesity was established with the body mass index (BMI) consigned in the woman's clinical file. Age and estrogen replacement therapy were included as co-variables. RESULTS: Seventy nine cases were identified and 237 controls were included. Obesity was observed in 54.4% of cases and in 41.3% of controls (odds ratio: 1.69; 95% confidence interval for odds ratio: 1.01-2.82; p value: 0.043). A logistic regression model including covariables maintained the observed association (p = 0.044). No association was found with analyzed co-variables. CONCLUSIONS: A false positive result in mammography was associated with the presence of obesity.
OBJECTIVE: To analyze the association between a false positive result in mammography and obesity, inside the breast cancer early detection program in women affiliated to the Institute of Security and Social Services for Government and Municipality workers of the State of Baja California (ISSSTECALI). MATERIAL AND METHODS: A case-control, retrospective study was done in women affiliated to ISSSTECALI to whom a mammography was performed between 2009 and 2012. Women with a false positive result in mammography were included as cases. Controls were women with a true negative result in mammography. Three controls were randomly selected for each case. Obesity was established with the body mass index (BMI) consigned in the woman's clinical file. Age and estrogen replacement therapy were included as co-variables. RESULTS: Seventy nine cases were identified and 237 controls were included. Obesity was observed in 54.4% of cases and in 41.3% of controls (odds ratio: 1.69; 95% confidence interval for odds ratio: 1.01-2.82; p value: 0.043). A logistic regression model including covariables maintained the observed association (p = 0.044). No association was found with analyzed co-variables. CONCLUSIONS: A false positive result in mammography was associated with the presence of obesity.
Authors: Annie Tang; Caitlin M Cohan; Keith S Hansen; Genna Beattie; Heather I Greenwood; Rita A Mukhtar Journal: Breast Cancer Res Treat Date: 2021-03-27 Impact factor: 4.872