Literature DB >> 27592166

Plasminogen deficiency is associated with improved glucose tolerance, and lower DPP-4 activity.

Yosuke Kanno1, Akane Sakai2, Mei Miyashita2, Kaho Tsuchida2, Osamu Matsuo3.   

Abstract

Plasminogen (Plg), which is the inactive form of plasmin, deficiency enhanced insulin secretion, and was associated with improved oral glucose tolerance in mice. Additionally, Plg deficiency was associated with lower dipeptidyl peptidase-4 (DPP-4) activity, and enhanced glucagons-like peptide-1 (GLP-1) expression. Plg may regulate the DPP-4 activity and the glucose metabolism.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  DPP-4; Glucose tolerance; Plasminogen

Mesh:

Substances:

Year:  2016        PMID: 27592166     DOI: 10.1016/j.diabres.2016.08.007

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  4 in total

1.  Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins.

Authors:  Estefanía Moreno; Júlia Canet; Eduard Gracia; Carme Lluís; Josefa Mallol; Enric I Canela; Antoni Cortés; Vicent Casadó
Journal:  Front Pharmacol       Date:  2018-02-15       Impact factor: 5.810

2.  Alternatively activated macrophages are associated with the α2AP production that occurs with the development of dermal fibrosis : The role of alternatively activated macrophages on the development of fibrosis.

Authors:  Yosuke Kanno; En Shu; Hirofumi Niwa; Hiroyuki Kanoh; Mariko Seishima
Journal:  Arthritis Res Ther       Date:  2020-04-10       Impact factor: 5.156

Review 3.  The Role of Fibrinolytic Regulators in Vascular Dysfunction of Systemic Sclerosis.

Authors:  Yosuke Kanno
Journal:  Int J Mol Sci       Date:  2019-01-31       Impact factor: 5.923

Review 4.  α2-Antiplasmin as a Potential Therapeutic Target for Systemic Sclerosis.

Authors:  Yosuke Kanno; En Shu
Journal:  Life (Basel)       Date:  2022-03-09
  4 in total

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