Literature DB >> 2759212

Age distribution of circulating alpha-interferon.

S Shiozawa1, K Shiozawa, S Shimizu, Y Tanaka, I Morimoto, Y Kuroki, R Yoshihara, T Fujita.   

Abstract

A sensitive radioimmunoassay showed that circulating alpha-interferon in the plasma of healthy individuals was low in children and reached the highest level in the young adult, then declined gradually with age. Circulating alpha-interferon was 0.201 +/- 0.059 ng/ml in males (n = 19) and 0.184 +/- 0.076 ng/ml in females (n = 14) at ages 30-39 years old. It was noted that circulating alpha-interferon was maintained up to a certain level even in elderly individuals.

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Year:  1989        PMID: 2759212     DOI: 10.1007/BF01974582

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  12 in total

1.  Dual mechanism of interferon augmentation of natural killer cytotoxicity (NKCC).

Authors:  S Targan; F Dorey
Journal:  Ann N Y Acad Sci       Date:  1980       Impact factor: 5.691

2.  Enhancement by interferon of lymphocyte cytotoxicity in normal individuals to cells of human lymphoblastoid lines.

Authors:  S V Skurkovich; A S Skorikova; E I Eremkina
Journal:  J Immunol       Date:  1978-09       Impact factor: 5.422

3.  Effects of interferon on leukaemia virus activation in graft versus host disease.

Authors:  M S Hirsch; D A Ellis; M R Proffitt; P H Black
Journal:  Nat New Biol       Date:  1973-07-25

4.  Inactivation of natural killer cell cytotoxic activity after interaction with target cells.

Authors:  B Perussia; G Trinchieri
Journal:  J Immunol       Date:  1981-02       Impact factor: 5.422

5.  A sensitive radioimmunoassay for alpha-interferon: circulating alpha-interferon-like substance in the plasma of healthy individuals and rheumatoid arthritis patients.

Authors:  S Shiozawa; K Chihara; K Shiozawa; T Fujita; H Ikegami; S Koyama; M Kurimoto
Journal:  Clin Exp Immunol       Date:  1986-10       Impact factor: 4.330

6.  Effects of metabolic inhibitors on spontaneous and interferon-boosted human natural killer cell activity.

Authors:  J R Ortaldo; W Phillips; K Wasserman; R B Herberman
Journal:  J Immunol       Date:  1980-10       Impact factor: 5.422

7.  Alpha-interferon treatment for adult T cell leukemia: low levels of circulating alpha-interferon and it's clinical effectiveness.

Authors:  K Saigo; S Shiozawa; K Shiozawa; J Wakuya; K Ueda; N Yamaguchi; H Shibata; T Masaoka
Journal:  Blut       Date:  1988-02

8.  A sensitive radioimmunoassay for circulating alpha-interferon in the plasma of healthy children and patients with measles virus infection.

Authors:  S Shiozawa; N Yoshikawa; K Iijima; K Negishi
Journal:  Clin Exp Immunol       Date:  1988-09       Impact factor: 4.330

9.  Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and antagonistic inhibition of susceptibility of target cells to lysis.

Authors:  G Trinchieri; D Santoli
Journal:  J Exp Med       Date:  1978-05-01       Impact factor: 14.307

10.  Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors.

Authors:  I Gresser; F Belardelli; C Maury; M T Maunoury; M G Tovey
Journal:  J Exp Med       Date:  1983-12-01       Impact factor: 14.307

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