Literature DB >> 27590683

Mortality Trends in Pediatric and Congenital Heart Surgery: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database.

Jeffrey P Jacobs1, Xia He2, John E Mayer3, Erle H Austin4, James A Quintessenza5, Tom R Karl6, Luca Vricella5, Constantine Mavroudis5, Sean M O'Brien2, Sara K Pasquali7, Kevin D Hill2, S Adil Husain8, David M Overman9, James D St Louis10, Jane M Han11, David M Shahian12, Duke Cameron5, Marshall L Jacobs5.   

Abstract

BACKGROUND: Previous analyses of The Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database have demonstrated a reduction over time of risk-adjusted operative mortality after coronary artery bypass grafting. The STS Congenital Heart Surgery Database (STS CHSD) was queried to assess multiinstitutional trends over time in discharge mortality and postoperative length of stay (PLOS).
METHODS: Since 2009, operations in the STS CHSD have been classified according to STAT (The Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery) Congenital Heart Surgery Mortality Categories. The five STAT Mortality Categories were chosen to be optimal with respect to minimizing variation within categories and maximizing variation between categories. For this study, all index cardiac operations from 1998 to 2014, inclusive, were grouped by STAT Mortality Category (exclusions: patent ductus arteriosus ligation in patients weighing less than or equal to 2.5 kg and operations that could not be assigned to a STAT Mortality Category). End points were discharge mortality and PLOS in survivors for the entire period and for 4-year epochs. The Cochran-Armitage trend test was used to test the null hypothesis that the mortality was the same across epochs, by STAT Mortality Category.
RESULTS: The analysis encompassed 202,895 index operations at 118 centers. The number of centers participating in STS CHSD increased in each epoch. Overall discharge mortality was 3.4% (6,959 of 202,895) for 1998 to 2014 and 3.1% (2,308 of 75,337) for 2011 to 2014. Statistically significant improvement in discharge mortality was seen in STAT Mortality Categories 2, 3, 4, and 5 (p values for STAT Mortality Categories 1 through 5 are 0.060, <0.001, 0.015, <0.001, and <0.001, respectively). PLOS in survivors was relatively unchanged over the same time intervals. Sensitivity analyses reveal that the finding of declining risk-stratified rates of discharge mortality over time is not simply attributable to the addition of more centers to the cohort over time.
CONCLUSIONS: This 16-year analysis of STS CHSD reveals declining discharge mortality over time, especially for more complex operations.
Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

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Mesh:

Year:  2016        PMID: 27590683     DOI: 10.1016/j.athoracsur.2016.01.071

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  19 in total

1.  Impact of pediatric cardiac surgery regionalization on health care utilization and mortality.

Authors:  Rie Sakai-Bizmark; Laurie A Mena; Hiraku Kumamaru; Ichiro Kawachi; Emily H Marr; Eliza J Webber; Hyun H Seo; Scott I M Friedlander; Ruey-Kang R Chang
Journal:  Health Serv Res       Date:  2019-03-27       Impact factor: 3.402

2.  Paediatric cardiopulmonary bypass surgery: the challenges of heterogeneity and identifying a meaningful endpoint for clinical trials.

Authors:  V J Pappachan; K L Brown; S M Tibby
Journal:  Intensive Care Med       Date:  2016-11-18       Impact factor: 17.440

3.  The Safe Addition of Nitric Oxide into the Sweep Gas of the Extracorporeal Circuit during Cardiopulmonary Bypass and Extracorporeal Life Support.

Authors:  Martin Bennett; Clarke Thuys; Simon Augustin; Brad Schultz; Steve Bottrell; Alison Horton; Andrzej Bednarz; Steve Horton
Journal:  J Extra Corpor Technol       Date:  2018-12

4.  Long-Term Risk of Heart Failure-Related Death and Heart Transplant After Congenital Heart Surgery in Childhood (from the Pediatric Cardiac Care Consortium).

Authors:  Lydia K Wright; Rachel Zmora; Yijian Huang; Matthew E Oster; Courtney McCracken; William T Mahle; Lazaros Kochilas; Andreas Kalogeropoulos
Journal:  Am J Cardiol       Date:  2022-01-03       Impact factor: 2.778

5.  Mid-regional pro-adrenomedullin for diagnosing evolution after cardiac surgery in newborns: the PRONEW study.

Authors:  Sara Bobillo-Perez; Monica Girona-Alarcon; Debora Cañizo; Marta Camprubi-Camprubi; Javier Rodriguez-Fanjul; Monica Balaguer; Sergio Benito; Anna Valls; Francisco Jose Cambra; Iolanda Jordan
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Review 6.  22q11.2 Deletion Syndrome: Impact of Genetics in the Treatment of Conotruncal Heart Defects.

Authors:  Carolina Putotto; Flaminia Pugnaloni; Marta Unolt; Stella Maiolo; Matteo Trezzi; Maria Cristina Digilio; Annapaola Cirillo; Giuseppe Limongelli; Bruno Marino; Giulio Calcagni; Paolo Versacci
Journal:  Children (Basel)       Date:  2022-05-25

7.  Characterization of "ICU-30": A Binary Composite Outcome for Neonates With Critical Congenital Heart Disease.

Authors:  Monique M Gardner; Garrett Keim; Jill Hsia; Anh D Mai; J William Gaynor; Andrew C Glatz; Nadir Yehya
Journal:  J Am Heart Assoc       Date:  2022-06-14       Impact factor: 6.106

8.  A Novel Model Demonstrates Variation in Risk-Adjusted Mortality Across Pediatric Cardiac ICUs After Surgery.

Authors:  Sarah Tabbutt; Jennifer Schuette; Wenying Zhang; Jeffrey Alten; Janet Donohue; J William Gaynor; Nancy Ghanayem; Jeffrey Jacobs; Sara K Pasquali; Ravi Thiagarajan; Justin B Dimick; Mousumi Banerjee; David Cooper; Michael Gaies
Journal:  Pediatr Crit Care Med       Date:  2019-02       Impact factor: 3.624

9.  Lower-Dose, Intravenous Chlorothiazide Is an Effective Adjunct Diuretic to Furosemide Following Pediatric Cardiac Surgery.

Authors:  Ryan J Carpenter; Shaghig Kouyoumjian; David Y Moromisato; Phuong Lieu; Rambod Amirnovin
Journal:  J Pediatr Pharmacol Ther       Date:  2020 Jan-Feb

Review 10.  American Society of ExtraCorporeal Technology: Development of Standards and Guidelines for Pediatric and Congenital Perfusion Practice (2019).

Authors:  Molly E Oldeen; Ronald E Angona; Ashley Hodge; Tom Klein
Journal:  J Extra Corpor Technol       Date:  2020-12
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