| Literature DB >> 27588730 |
Kathrin Wittstein1,2, Monique Rascher3, Zeljka Rupcic1,2, Eduard Löwen1,2, Barbara Winter3, Reinhard W Köster3, Marc Stadler1,2.
Abstract
Three new natural products, corallocins A-C (1-3), along with two known compounds were isolated from the mushroom Hericium coralloides. Their benzofuranone and isoindolinone structures were elucidated by spectral methods. All corallocins induced nerve growth factor and/or brain-derived neurotrophic factor expression in human 1321N1 astrocytes. Furthermore, corallocin B showed antiproliferative activity against HUVEC and human cancer cell lines MCF-7 and KB-3-1.Entities:
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Year: 2016 PMID： 27588730 DOI： 10.1021/acs.jnatprod.6b00371
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050