Literature DB >> 27585115

The acute anorexic effect of liraglutide, a GLP-1 receptor agonist, does not require functional leptin receptor, serotonin, and hypothalamic POMC and CART activities in mice.

Katsunori Nonogaki1, Takao Kaji2.   

Abstract

The acute anorexic effect of liraglutide, a GLP-1 receptor agonist, did not require functional leptin receptor, serotonin, and hypothalamic proopiomelanocortin and cocaine amphetamine regulated transcript activities in mice, although decrease in functional hypothalamic orexin activity might be involved in the acute anorexic effect of liraglutide.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  5-HT; Food intake; GLP-1 receptor; Liraglutide; Orexin; POMC

Mesh:

Substances:

Year:  2016        PMID: 27585115     DOI: 10.1016/j.diabres.2016.08.009

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN: 0168-8227            Impact factor:   5.602


  7 in total

1.  Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway.

Authors:  Cecilia Ratner; Zhenyan He; Kaare V Grunddal; Louise J Skov; Bolette Hartmann; Fa Zhang; Annette Feuchtinger; Anette Bjerregaard; Christina Christoffersen; Matthias H Tschöp; Brian Finan; Richard D DiMarchi; Gina M Leinninger; Kevin W Williams; Christoffer Clemmensen; Birgitte Holst
Journal:  Diabetes       Date:  2019-04-01       Impact factor: 9.461

2.  Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight.

Authors:  Rozita H Anderberg; Jennifer E Richard; Kim Eerola; Lorena López-Ferreras; Elin Banke; Caroline Hansson; Hans Nissbrandt; Filip Berqquist; Fiona M Gribble; Frank Reimann; Ingrid Wernstedt Asterholm; Christophe M Lamy; Karolina P Skibicka
Journal:  Diabetes       Date:  2017-01-05       Impact factor: 9.461

3.  The Effects of Mutual Interaction of Orexin-A and Glucagon-Like Peptide-1 on Reflex Swallowing Induced by SLN Afferents in Rats.

Authors:  Motoi Kobashi; Yuichi Shimatani; Masako Fujita; Yoshihiro Mitoh; Ryusuke Yoshida; Ryuji Matsuo
Journal:  Int J Mol Sci       Date:  2020-06-22       Impact factor: 5.923

Review 4.  The Regulatory Role of the Central and Peripheral Serotonin Network on Feeding Signals in Metabolic Diseases.

Authors:  Katsunori Nonogaki
Journal:  Int J Mol Sci       Date:  2022-01-29       Impact factor: 5.923

5.  Liraglutide, a GLP-1 Receptor Agonist, Which Decreases Hypothalamic 5-HT2A Receptor Expression, Reduces Appetite and Body Weight Independently of Serotonin Synthesis in Mice.

Authors:  Katsunori Nonogaki; Takao Kaji
Journal:  J Diabetes Res       Date:  2018-02-01       Impact factor: 4.011

6.  Capsaicin has an anti-obesity effect through alterations in gut microbiota populations and short-chain fatty acid concentrations.

Authors:  Yuanwei Wang; Cheng Tang; Yong Tang; Haiyan Yin; Xiong Liu
Journal:  Food Nutr Res       Date:  2020-02-19       Impact factor: 3.894

7.  A Single Dose of Ginkgo biloba Extract Induces Gene Expression of Hypothalamic Anorexigenic Effectors in Male Rats.

Authors:  Meira M F Machado; Janilda P Pereira; Bruna K S Hirata; Viviane S Júlio; Renata M Banin; Heider M Andrade; Eliane B Ribeiro; Suzete M Cerutti; Mônica M Telles
Journal:  Brain Sci       Date:  2021-12-02
  7 in total

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