Literature DB >> 27582868

Uric acid: is it time to give up routine testing in management of pre-eclampsia?

Vikram Sinai Talaulikar1, Hassan Shehata2.   

Abstract

Ever since it was first linked with the pathophysiology of pre-eclampsia, uric acid has been a routine test requested by many care-givers managing pregnant women with hypertensive disease of pregnancy for almost 100 years. Existing evidence however suggests that it has no definitive role in prediction, diagnosis or management of pre-eclampsia. We argue against routine uric acid testing in pregnancies complicated by hypertension not only because it has become a fruitless academic exercise but also because ceasing its routine use will ensure cost-savings for the health services.

Entities:  

Keywords:  gestational hypertension; investigations; pre-eclampsia; uric acid

Year:  2012        PMID: 27582868      PMCID: PMC4989702          DOI: 10.1258/om.2011.110075

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  55 in total

1.  Relation between serum uric acid and plasma adenosine levels in women with preeclampsia.

Authors:  S Suzuki; Y Yoneyama; R Sawa; Y Otsubo; T Takeuchi; T Araki
Journal:  Gynecol Obstet Invest       Date:  2001       Impact factor: 2.031

2.  Perinatal outcome in pregnancy induced hypertension.

Authors:  K B Gupta; I Randhawa; A Pal; H K Premi; J Ganeshan
Journal:  J Indian Med Assoc       Date:  1996-01

3.  Are high uric acid levels in patients with early pre-eclampsia an indication for delivery?

Authors:  H J Odendaal; M E Pienaar
Journal:  S Afr Med J       Date:  1997-02

4.  Uric acid is as important as proteinuria in identifying fetal risk in women with gestational hypertension.

Authors:  James M Roberts; Lisa M Bodnar; Kristine Y Lain; Carl A Hubel; Nina Markovic; Roberta B Ness; Robert W Powers
Journal:  Hypertension       Date:  2005-10-24       Impact factor: 10.190

5.  Risk indicators for eclampsia in gestational hypertension or mild preeclampsia at term.

Authors:  Corine M Koopmans; Joost J Zwart; Henk Groen; Kitty W M Bloemenkamp; Ben W J Mol; Maria G Van Pampus; Jos Van Roosmalen
Journal:  Hypertens Pregnancy       Date:  2010-09-07       Impact factor: 2.108

6.  High uric acid level during the first 20 weeks of pregnancy is associated with higher risk for gestational diabetes mellitus and mild preeclampsia.

Authors:  Talya Wolak; Ruslan Sergienko; Arnon Wiznitzer; Esther Paran; Eyal Sheiner
Journal:  Hypertens Pregnancy       Date:  2010-09-07       Impact factor: 2.108

7.  Poor predictive value of platelet count, mean platelet volume and serum urate in hypertension in pregnancy.

Authors:  S M Calvert; D J Tuffnell; J Haley
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1996-02       Impact factor: 2.435

8.  Risk grouping of 113 patients with hypertensive disorders during pregnancy, with respect to serum urate, proteinuria and time of onset of hypertension.

Authors:  H Liedholm; S Montan; A Aberg
Journal:  Acta Obstet Gynecol Scand Suppl       Date:  1984

9.  Effect of fetal number on maternal serum uric acid concentration.

Authors:  Shlomo B Cohen; Doron Kreiser; Izhar Erez; Inna Kogan; Daniel S Seidman; Eyal Schiff
Journal:  Am J Perinatol       Date:  2002-08       Impact factor: 1.862

10.  Plasma urate measurements and fetal outcome in preeclampsia.

Authors:  E Schuster; B Weppelmann
Journal:  Gynecol Obstet Invest       Date:  1981       Impact factor: 2.031

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